ArticlePlant signaling & behavior2018
The Arabidopsis Mitogen-Activated Protein Kinase Kinase Kinase 20 (MKKK20) C-terminal domain interacts with MKK3 and harbors a typical DEF mammalian MAP kinase docking site.
Article in Plant signaling & behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Interactome of Arabidopsis Thaliana.Plants (Basel, Switzerland) · 2022Article
- Rice calcium/calmodulin-dependent protein kinase directly phosphorylates a mitogen-activated protein kinase kinase to regulate abscisic acid responses.The Plant cell · 2021Article
- Plant Mitogen-Activated Protein Kinase Cascades in Environmental Stresses.International journal of molecular sciences · 2021Review
- The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development.BMC plant biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitogen-activated protein kinase (MAPKs) constitute a major component in plant cellular signaling considering the sheer number of MAPKKKKs, MAPKKKs, MAPKKs and MAPKs when compared to yeast and animal systems. Nevertheless, only few complete MAPK cascades have been deciphered and the same hold true for their substrates. Furthermore, cascades often share kinase components, but little is known about their specific interactions and domains. The Arabidopsis thaliana MAP kinase kinase kinase 20 (MKKK20) was recently showed to interact with MKK3 and MPK18 in two non-complementary signaling cascades involved in root cortical microtubule functions. Here, MKKK20 and MKK3 proteins where dissected and tested in yeast two-hybrid assays followed by an in planta validation through bimolecular fluorescence complementation (BiFC) assays and showed that the MKKK20 C-terminal region interacted with MKK3 that comprised a typical DEF domain akin to MAPKs docking domains.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.