Evidence map›Paper›PMID 30081693›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2019

Flow diverter for endovascular treatment of intracranial mirror segment internal carotid artery aneurysms.

Anna Luisa Kühn, Peter Kan, Visish Srinivasan, David E Rex, Katyucia de Macedo Rodrigues, Mary C Howk, Ajay K Wakhloo, Ajit S Puri

Open access · bronzeAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anna Luisa Kühn1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.ORCID https://orcid.org/0000-0001-9512-9461
Peter Kan2 Department of Neurosurgery, Baylor College of Medicine, Houston, USA.ORCID https://orcid.org/0000-0002-6224-097X
Visish Srinivasan2 Department of Neurosurgery, Baylor College of Medicine, Houston, USA.
David E Rex1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.
Katyucia de Macedo Rodrigues1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.
Mary C Howk1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.
Ajay K Wakhloo1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.
Ajit S Puri1 Department of Radiology and New England Center for Stroke Research, University of Massachusetts, Worcester, USA.
Baylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the feasibility and efficacy of the pipeline embolization device in the treatment of unruptured intracranial mirror segment aneurysms.

methodsOut of a total of 338 subjects, 14 were identified harboring a total of 32 internal carotid artery mirror segment aneurysms that were treated with the pipeline embolization device and were consecutively enrolled into our study. We collected data on patient demographics, modified Rankin scale (mRS) at admission, aneurysm characteristics, clinical outcome at discharge, 3-9 and at 12-18 months as well as angiography results at follow-up.

resultsPatients' mean age was 52.9 years; baseline mRS was 0 in all subjects. Pipeline embolization device placement was successful in all cases. Post-treatment mRS remained 0 in 13/14 patients. One patient experienced a small intraparenchymal hemorrhage and subarachnoid hemorrhage, associated with a frontoparietal infarction resulting in right upper extremity weakness and aphasia (post-treatment mRS 3). His mRS evaluation remained stable at the 3-9-month follow-up. Three to 9-month follow-up angiography (13/14 subjects) showed complete aneurysm occlusion in 24/30 aneurysms (80%), near complete and partial occlusion in three of 30 (10%) aneurysms each. At the 9-month follow-up, one patient experienced a complete occlusion of the anterior temporal artery branch but did not present with any clinical deficits. No mRS changes were encountered over a median 6-month follow-up period. Mid-term follow-up angiography (12-18 months) available in eight of 14 subjects showed complete aneurysm occlusion in all patients. Mild intimal hyperplasia was observed in one patient.

conclusionsFlow diversion technology can be used for the treatment of unruptured mirror segment aneurysms in selected patients.

Indexed as

Carotid Artery, InternalStentsAdultAgedCone-Beam Computed TomographyEmbolization, TherapeuticFeasibility StudiesFemaleHumansIntracranial AneurysmMaleMiddle AgedRadiography, InterventionalRetrospective StudiesTreatment OutcomeEndovascular treatmentflow divertermirror segment aneurysmspipeline embolization device

Identifiers

PMID30081693
PMCPMC6378532
OpenAlexW2885735508

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.