Evidence map›Paper›PMID 30081604›Full record

ArticleInternational journal of molecular sciences2018

The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression.

Jaehyuk Pyo, Jaewook Ryu, Wootae Kim, Jae-Sun Choi, Joo-Won Jeong, Ja-Eun Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jaehyuk PyoDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. biopyo37@naver.com.
Jaewook RyuDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. busterray@naver.com.
Wootae KimDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. mubear@khu.ac.kr.
Jae-Sun ChoiDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. jaesun0505@naver.com.ORCID 0000-0003-2069-3361
Joo-Won JeongDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. jjeong@khu.ac.kr.
Ja-Eun KimDepartment of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Korea. jekim@khu.ac.kr.ORCID 0000-0002-9132-1277
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia-inducible factors (HIFs) are key regulators of hypoxic responses, and their stability and transcriptional activity are controlled by several kinases. However, the regulation of HIF by protein phosphatases has not been thoroughly investigated. Here, we found that overexpression of Mg

Indexed as

Blotting, WesternCell HypoxiaHEK293 CellsHumansHypoxia-Inducible Factor 1, alpha SubunitOxidative StressProtein BindingProtein Phosphatase 2CReverse Transcriptase Polymerase Chain ReactionVon Hippel-Lindau Tumor Suppressor ProteinHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitProtein Phosphatase 2CVon Hippel-Lindau Tumor Suppressor ProteinHIF-1αhypoxianormoxiaPPM1G

Identifiers

PMID30081604
PMCPMC6121667
OpenAlexW2886536765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.