Evidence map›Paper›PMID 30081588›Full record

ArticleInternational journal of environmental research and public health2018

Micronuclei in Exfoliated Buccal Cells of Children Living in a Cluster Area of Salento (Southern Italy) with a High Incidence of Lung Cancer: The IMP.AIR Study.

Adele Idolo, Tiziana Grassi, Francesco Bagordo, Alessandra Panico, Mattia De Giorgi, Francesca Serio, Marcello Guido, Prisco Piscitelli, Giovanni De Filippis, Annamaria Raho and 1 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adele IdoloDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. adele.idolo@unisalento.it.ORCID 0000-0002-6049-1986
Tiziana GrassiDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. tiziana.grassi@unisalento.it.
Francesco BagordoDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. francesco.bagordo@unisalento.it.ORCID 0000-0001-5208-5382
Alessandra PanicoDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. alessandra.panico@unisalento.it.
Mattia De GiorgiDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. mattia.degiorgi@unisalento.it.
Francesca SerioDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. francesca.serio@unisalento.it.ORCID 0000-0002-2782-2798
Marcello GuidoDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. marcello.guido@unisalento.it.
Prisco PiscitelliLocal Health Authority ASL LE, 73100 Lecce, Italy. priscofreedom@hotmail.com.ORCID 0000-0003-4556-6182
Giovanni De FilippisLocal Health Authority ASL LE, 73100 Lecce, Italy. giov.defilippis@gmail.com.
Annamaria RahoLocal Health Authority ASL LE, 73100 Lecce, Italy. annamaria.raho@gmail.com.
Antonella De DonnoDepartment of Biological and Environmental Science and Technology, University of Salento, via Monteroni 165, 73100 Lecce, Italy. antonella.dedonno@unisalento.it.ORCID 0000-0001-8349-2466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the years 2014⁻2016 the University of Salento performed the "Impact of Air Quality on Health of Residents in the Municipalities of Cutrofiano, Galatina, Sogliano Cavour, Soleto and Sternatia" (IMP.AIR) study, an epidemiological-molecular research project aiming to evaluate early DNA damage in children living in an area of Salento with high incidence of lung cancer among the male population. One hundred and twenty-two children aged 6⁻8 years attending primary school were enrolled and the frequency of micronucleated cells (MNC) in oral mucosa was evaluated. In addition, a questionnaire was administered to parents to obtain information about personal data, anthropometric characteristics and lifestyles (physical activity, food habits, family context) of the children and perform a multivariate analysis to detect any factors associated with MNC occurrence. Data on airborne pollutants detected in the study area were acquired by the Regional Agency for the Environmental Protection. The presence of MNC was highlighted in about 42% of children with a mean MNC frequency of 0.49‰. The frequency of MNC was associated to obesity, consumption of red or processed meat and having a mother who smokes. Moreover, the prevalence of biomarkers was higher than in another area of Salento not included in the cluster area.

Indexed as

DNA DamageChildEnvironmental ExposureEnvironmental MonitoringFemaleHumansItalyLife StyleMaleMicronucleus TestsMouth Mucosachildrenexfoliated buccal cellsIMP.AIR studymicronucleusSalento

Identifiers

PMID30081588
PMCPMC6121539

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.