Evidence map›Paper›PMID 30081564›Full record

ArticleMarine drugs2018

Chemical Mutagenesis and Fluorescence-Based High-Throughput Screening for Enhanced Accumulation of Carotenoids in a Model Marine Diatom Phaeodactylum tricornutum.

Zhiqian Yi, Yixi Su, Maonian Xu, Andreas Bergmann, Saevar Ingthorsson, Ottar Rolfsson, Kourosh Salehi-Ashtiani, Sigurdur Brynjolfsson, Weiqi Fu

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 50 citations in OpenAlex.

  1. Marine drugs · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Characterization ofMicroorganisms · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Improvement and screening of astaxanthin producing mutants of newly isolatedBiotechnology reports (Amsterdam, Netherlands) · 2021
    Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Zhiqian YiCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. zhy1@hi.is.ORCID 0000-0001-7761-8413
Yixi SuCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. yis2@hi.is.
Maonian XuFaculty of Pharmaceutical Sciences, University of Iceland, Hagi, Hofsvallagata 53, 107 Reykjavik, Iceland. maonian@hi.is.
Andreas BergmannCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. andreasbergmannhome@gmail.com.ORCID 0000-0001-8006-4888
Saevar IngthorssonBiomedical Center and Department of Anatomy, Faulty of Medicine, University of Iceland, 101 Reykjavík, Iceland. saevari@hi.is.
Ottar RolfssonCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. ottarr@hi.is.
Kourosh Salehi-AshtianiDivision of Science and Math, and Center for Genomics and Systems Biology (CGSB), New York University Abu Dhabi, Abu Dhabi 129188, UAE. ksa3@nyu.edu.ORCID 0000-0002-6521-5243
Sigurdur BrynjolfssonCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. sb@hi.is.ORCID 0000-0001-9435-2258
Weiqi FuCenter for Systems Biology and Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, School of Engineering and Natural Sciences, University of Iceland, 101 Reykjavík, Iceland. weiqi@hi.is.ORCID 0000-0002-7368-383X
University of Iceland · ISNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diatoms are a major group of unicellular algae that are rich in lipids and carotenoids. However, sustained research efforts are needed to improve the strain performance for high product yields towards commercialization. In this study, we generated a number of mutants of the model diatom

Indexed as

Aquatic OrganismsCarotenoidsChlorophyllChlorophyll AChromatography, LiquidDiatomsEthyl MethanesulfonateFluorescenceHigh-Throughput Screening AssaysLipid MetabolismLipidsMetabolic Networks and PathwaysMethylnitronitrosoguanidineMutagenesisCarotenoidsChlorophyllChlorophyll AEthyl MethanesulfonateLipidsMethylnitronitrosoguanidinecarotenoidsdiatomEMSfucoxanthinmutagenesisscreening

Identifiers

PMID30081564
PMCPMC6117690
OpenAlexW2886683907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.