ArticleMarine drugs2018
Novel Natural Angiotensin Converting Enzyme (ACE)-Inhibitory Peptides Derived from Sea Cucumber-Modified Hydrolysates by Adding Exogenous Proline and a Study of Their Structure⁻Activity Relationship.
Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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Who cites it
24 citing papers in PubMed.
- Preparation, Characterization, and pH-Responsive Intestinal Release Properties of Gel Beads Encapsulating Sea Cucumber Mouthpart Peptides.Marine drugs · 2026Article
- Antihypertensive Peptides and Hydrolysates Derived from Plant Proteins and Their Bioavailability.Foods (Basel, Switzerland) · 2026Review
- Peptidomics-based identification of endogenous free peptides fromFrontiers in pharmacology · 2026Article
- Effect of Plastein Reaction on Physical and Chemical Characteristics of Corn Glutelin Peptides and Quality of Chiffon Cake.Foods (Basel, Switzerland) · 2025Article
- Molecular insights into the inhibition of angiotensin-converting enzyme 1 by hemopressin peptides.Scientific reports · 2024Article
- Marine-Derived Peptides with Anti-Hypertensive Properties: Prospects for Pharmaceuticals, Supplements, and Functional Food.Marine drugs · 2024Review
- Marine sourced tripeptide SRP and its sustained-release formulation SRP-PLGA-MS exhibiting antihypertensive effect in spontaneously hypertensive rats and HUVECs.Frontiers in nutrition · 2024Article
- The Nutritional and Functional Properties of Protein Isolates from Defatted Chia Flour Using Different Extraction pH.Foods (Basel, Switzerland) · 2023Article
- Antioxidant and ACE-Inhibitory Activity of Protein Hydrolysates Produced from Atlantic Sea Cucumber (Molecules (Basel, Switzerland) · 2023Article
- Research progress on the chemical components and biological activities of sea cucumber polypeptides.Frontiers in pharmacology · 2023Review
- Ameliorative Effects of Peptide Phe-Leu-Ala-Pro on Acute Liver and Kidney Injury Caused by CClACS omega · 2022Article
- Evaluation of Biological Activity of Natural Compounds: Current Trends and Methods.Molecules (Basel, Switzerland) · 2022Review
- Impact of the Plastein Reaction of Casein Hydrolysates in the Presence of Exogenous Amino Acids on Their Anti-Inflammatory Effect in the Lipopolysaccharide-Stimulated Macrophages.Foods (Basel, Switzerland) · 2022Article
- A Novel Angiotensin-I-Converting Enzyme (ACE) Inhibitory Peptide fromMarine drugs · 2021Article
- Lupin-Derived Bioactive Peptides: Intestinal Transport, Bioavailability and Health Benefits.Nutrients · 2021Review
- Two novel potent ACEI peptides isolated fromRSC advances · 2021Article
- Cardiovascular Active Peptides of Marine Origin with ACE Inhibitory Activities: Potential Role as Anti-Hypertensive Drugs and in Prevention of SARS-CoV-2 Infection.International journal of molecular sciences · 2020Review
- Targeting eukaryotic proteases for natural products-based drug development.Natural product reports · 2020Review
- Improvement of chicken plasma protein hydrolysate angiotensin I-converting enzyme inhibitory activity by optimizing plastein reaction.Food science & nutrition · 2020Article
- Anti-Hypertensive Activity of Novel Peptides Identified from Olive Flounder (Foods (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural angiotensin converting enzyme (ACE)-inhibitory peptides, which are derived from marine products, are useful as antihypertensive drugs. Nevertheless, the activities of these natural peptides are relatively low, which limits their applications. The aim of this study was to prepare efficient ACE-inhibitory peptides from sea cucumber-modified hydrolysates by adding exogenous proline according to a facile plastein reaction. When 40% proline (
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