Evidence map›Paper›PMID 30081552›Full record

ArticleInternational journal of molecular sciences2018

Differences in Functional Expression of Connexin43 and Na

Xian Zhang, Dakshesh Patel, Qin Xu, Richard Veenstra

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xian ZhangDepartment of Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA. ZhangXi@upstate.edu.ORCID 0000-0002-6548-032X
Dakshesh PatelDepartment of Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA. daksheshpatel10@gmail.com.ORCID 0000-0002-6507-9771
Qin XuDepartment of Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA. xuqinblue@gmail.com.
Richard VeenstraDepartment of Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA. veenstrr@upstate.edu.
SUNY Upstate Medical University · US

Funding

GAP JUNCTIONS AND IONIC CURRENTS IN DEVELOPING HEARTR01HL042220 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI VEENSTRA, RICHARD DAVID, YANG, JENNY J. · 1988 to 2013
$3.1M
NHLBI NIH HHS R01 HL042220
6 · The paper itself

Abstract

Class-selective histone deacetylase (HDAC) inhibitors were designed to improve safety profiles and therapeutic effectiveness in the treatment of multiple cancers relative to pan-HDAC inhibitors. However, the underlying mechanisms for their therapeutic and cardiotoxic potentials remain poorly understood. Cardiac sodium currents (I

Indexed as

AnimalsBenzamidesBlotting, WesternCells, CulturedConnexin 43Gap JunctionsHistone Deacetylase InhibitorsHydroxamic AcidsIndolesMiceMice, Inbred C57BLMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelPanobinostatPatch-Clamp TechniquesPyridinesBenzamidesConnexin 43entinostatHistone Deacetylase InhibitorsHydroxamic AcidsIndolesNAV1.5 Voltage-Gated Sodium ChannelPanobinostatPyridinesPyrimidinesricolinostatcardiac sodium channelcardiotoxicityclass-selectiveconnexin43gap junctionhistone deacetylase inhibitorsNaV1.5

Identifiers

PMID30081552
PMCPMC6121244
OpenAlexW2885369001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.