Evidence map›Paper›PMID 30081517›Full record

ReviewNutrients2018

Retinoic Acid, Leaky Gut, and Autoimmune Diseases.

Leila Abdelhamid, Xin M Luo

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Retinoic acid signaling and metabolism in heart failure.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  7. Review
  8. Review
  9. Lipocalin-2 and intestinal diseases.World journal of gastroenterology · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Retinoic Acid Signaling in Fatty Liver Disease.Liver research (Beijing, China) · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Leila AbdelhamidDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA. leila88@vt.edu.
Xin M LuoDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA. xinluo@vt.edu.ORCID 0000-0002-2809-5836
Virginia–Maryland College of Veterinary Medicine · US

Funding

Mechanistic role of probiotic Lactobacillus reuteri in autoimmune lupusR01AR073240 · NIAMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LUO, XIN · 2018 to 2022
$1.7M
Dissecting the Roles of Vitamin A in AutoimmunityR15AR067418 · NIAMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LUO, XIN · 2017 to 2017
$451k
NIAMS NIH HHS R01 AR073240NIAMS NIH HHS R15 AR067418
6 · The paper itself

Abstract

A leaky gut has been observed in a number of autoimmune diseases including type 1 diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus erythematosus. Previous studies from our laboratory have shown that lupus mice also bear a leaky gut and that the intestinal barrier function can be enhanced by gut colonization of probiotics such as

Indexed as

AnimalsAutoimmune DiseasesAutoimmunityBacteriaGastrointestinal MicrobiomeHost-Pathogen InteractionsHumansImmunologic FactorsIntestinesPermeabilityTreatment OutcomeTretinoinImmunologic FactorsTretinoinautoimmune diseasesleaky gutretinoic acid

Identifiers

PMID30081517
PMCPMC6115935
OpenAlexW2885284099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.