Evidence map›Paper›PMID 30081502›Full record

ReviewNutrients2018

Extraintestinal Manifestations of Celiac Disease: Early Detection for Better Long-Term Outcomes.

Pilvi Laurikka, Samuli Nurminen, Laura Kivelä, Kalle Kurppa

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 5 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 5 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
  9. From Villi to Alveoli: Lung Involvement in Celiac Disease - A Narrative Review.Journal of community hospital internal medicine perspectives · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Celiac Disease: Beyond Diet and Food Awareness.Foods (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Pilvi LaurikkaCeliac Disease Research Center, Faculty of Medicine and Life Sciences, University of Tampere, 33014 Tampere, Finland. laurikka.pilvi.l@student.uta.fi.
Samuli NurminenTampere Center for Child Health Research, Tampere University Hospital and University of Tampere, 33014 Tampere, Finland. nurminen.samuli.j@student.uta.fi.
Laura KiveläTampere Center for Child Health Research, Tampere University Hospital and University of Tampere, 33014 Tampere, Finland. laura.kivela@fimnet.fi.
Kalle KurppaTampere Center for Child Health Research, Tampere University Hospital and University of Tampere, 33014 Tampere, Finland. kalle.kurppa@uta.fi.
Tampere University Hospital · FITampere University · FITampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population-based screening studies have shown celiac disease to be one of the most common chronic gastrointestinal diseases. Nevertheless, because of the diverse clinical presentation, the great majority of patients remain unrecognized. Particularly difficult to identify are the multifaceted extraintestinal symptoms that may appear at variable ages. Although the pathogenesis and long-term outcome of these manifestations are still poorly established, there is some evidence that unrecognized celiac disease predisposes to severe complications if not diagnosed and prevented with an early-initiated gluten-free diet. Therefore, it is of utmost importance that physicians of different disciplines learn to recognize celiac disease in individuals with non-gastrointestinal symptoms. In the future, more studies are needed to clarify the factors affecting development and prognosis of the extraintestinal manifestations.

Indexed as

Celiac DiseaseDiet, Gluten-FreeEarly DiagnosisHumansPredictive Value of TestsPrognosisRisk FactorsTime Factorsceliac diseaseclinical presentationdiagnosisextraintestinalgluten-free dietprognosisrecognition

Identifiers

PMID30081502
PMCPMC6115849
OpenAlexW2887735446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.