Evidence map›Paper›PMID 30081303›Full record

ArticleBiomaterials2018

Micropatterned cell sheets as structural building blocks for biomimetic vascular patches.

Nae Gyune Rim, Alice Yih, Peter Hsi, Yunjie Wang, Yanhang Zhang, Joyce Y Wong

Abstract read
In one paragraph

Article in Biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Advances in tissue engineering and biofabrication forBioprinting (Amsterdam, Netherlands) · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Recent Progress inFrontiers in cardiovascular medicine · 2021
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nae Gyune RimDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Alice YihDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Peter HsiDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Yunjie WangDepartment of Mechanical Engineering, and Boston University, Boston, MA 02215, USA.
Yanhang ZhangDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA; Department of Mechanical Engineering, and Boston University, Boston, MA 02215, USA; Division of Materials Science and Engineering, Boston University, Boston, MA 02215, USA.
Joyce Y WongDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA; Division of Materials Science and Engineering, Boston University, Boston, MA 02215, USA. Electronic address: jywong@bu.edu.

Funding

Multi-Scale Integration of Extracellular Matrix Mechanics in Vascular RemodelingR01HL098028 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI ZHANG, YANHANG KATHERINE · 2011 to 2025
$5.2M
NHLBI NIH HHS R01 HL098028
6 · The paper itself

Abstract

To successfully develop a functional tissue-engineered vascular patch, recapitulating the hierarchical structure of vessel is critical to mimic mechanical properties. Here, we use a cell sheet engineering strategy with micropatterning technique to control structural organization of bovine aortic vascular smooth muscle cell (VSMC) sheets. Actin filament staining and image analysis showed clear cellular alignment of VSMC sheets cultured on patterned substrates. Viability of harvested VSMC sheets was confirmed by Live/Dead

Indexed as

AnimalsBiomimeticsCattleCells, CulturedCollagenFinite Element AnalysisHydrogel, Polyethylene Glycol DimethacrylateMuscle, Smooth, VascularMyocytes, Smooth MuscleTissue EngineeringCollagenHydrogel, Polyethylene Glycol DimethacrylateCell sheetFinite element modelingHydrogelPatterningTensile testingVascular smooth muscle cell

Identifiers

PMID30081303
PMCPMC6661166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.