ArticleThe Journal of head trauma rehabilitation
Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage.
Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Occupational and domestic exposure associations with cerebral small vessel disease and vascular dementia: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Magnetic Resonance Spectroscopy of Traumatic Brain Injury and Subconcussive Hits: A Systematic Review and Meta-Analysis.Journal of neurotrauma · 2022Pooled it
- A global collaboration to study intimate partner violence-related head trauma: The ENIGMA consortium IPV working group.Brain imaging and behavior · 2021Pooled it
- Systematic Review of the Long-Term Neuroimaging Correlates of Mild Traumatic Brain Injury and Repetitive Head Injuries.Frontiers in neurology · 2021Pooled it
- Characteristic patterns of white matter tract injury in sport-related concussion: An image based meta-analysis.NeuroImage. Clinical · 2020Pooled it
- Population-referenced multiregional brain-volume profiles associated with performance and concussion history in athletes: an exploratory study.Frontiers in human neuroscience · 2026Article
- Dose-dependent white matter changes associated with repetitive head impacts in former American football players.Brain communications · 2026Article
- The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure.Human brain mapping · 2025Article
- Long-term neurobehavioral and neuroimaging outcomes in athletes with prior concussion(s) and head impact exposure.The Clinical neuropsychologist · 2025Review
- Improving quantitative susceptibility mapping for the identification of traumatic brain injury neurodegeneration at the individual level.Zeitschrift fur medizinische Physik · 2025Article
- Traumatic Brain Injury and Chronic Traumatic Encephalopathy: Not Only Trigger for Neurodegeneration but Also for Cerebral Amyloid Angiopathy?Biomedicines · 2025Review
- Investigating the Association of Concussion and Contact Sport Exposure History With Brain Microstructure Using Quantitative Susceptibility Mapping.Human brain mapping · 2025Article
- Characterizing positive and negative quantitative susceptibility values in the cortex following mild traumatic brain injury: a depth- and curvature-based study.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Does white matter and vascular injury from repetitive head impacts lead to a novel pattern on T2 FLAIR MRI? A hypothesis proposal and call for research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Mild traumatic brain injury increases cortical iron: evidence from individual susceptibility mapping.Brain communications · 2025Article
- White matter hyperintensities in former American football players.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts.Brain communications · 2023Article
- Multimodal magnetic resonance imaging of youth sport-related concussion reveals acute changes in the cerebellum, basal ganglia, and corpus callosum that resolve with recovery.Frontiers in human neuroscience · 2022Article
- Quantifying and Examining Reserve in Symptomatic Former National Football League Players.Journal of Alzheimer's disease : JAD · 2022Article
- Identifying degenerative effects of repetitive head trauma with neuroimaging: a clinically-oriented review.Acta neuropathologica communications · 2021Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundLong-term consequences of playing professional football and hockey on brain function and structural neuronal integrity are unknown.
objectivesTo investigate multimodal metabolic and structural brain magnetic resonance imaging (MRI) differences in retired professional contact sport athletes compared with noncontact sport athletes.
methodsTwenty-one male contact sport athletes and 21 age-matched noncontact sport athletes were scanned on a 3 tesla (3T) MRI using a multimodal imaging approach. The MRI outcomes included presence, number, and volume of focal white matter signal abnormalities, volumes of global and regional tissue-specific brain structures, diffusion-tensor imaging tract-based spatial statistics measures of mean diffusivity and fractional anisotropy, quantitative susceptibility mapping of deep gray matter, presence, number, and volume of cerebral microbleeds, MR spectroscopy N-acetyl-aspartate, glutamate, and glutamine concentrations relative to creatine and phosphor creatine of the corpus callosum, and perfusion-weighted imaging mean transit time, cerebral blood flow, and cerebral blood volume outcomes. Subjects were also classified as having mild cognitive impairment.
resultsNo significant differences were found for structural or functional MRI measures between contact sport athletes and noncontact sport athletes.
conclusionsThis multimodal imaging study did not show any microstructural, metabolic brain tissue injury differences in retired contact versus non-contact sport athletes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.