ReviewThe Journal of allergy and clinical immunology2018
Innate and adaptive immune responses to fungi in the airway.
Review in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Association between sensitization to common fungi and severe asthma.Frontiers in public health · 2025Pooled it
- Invasive aspergillosis in autoimmune inflammatory rheumatic diseases: epidemiology, risk factors, diagnosis, management and challenges.Annals of medicine · 2026Review
- Coccidioidomycosis in Patients Treated with Dupilumab: A Descriptive Case Series.Mycopathologia · 2026Article
- Active protein-capturing hydrogel for broad-spectrum pathogen defense.Science advances · 2026Article
- Fungal exposure exacerbates allergen-driven asthma in a two-hit mouse model.Respiratory research · 2026Article
- The Impact of Extreme Weather Events on Allergic Airway Disease.Current allergy and asthma reports · 2026Review
- Fungal Frontiers in (Bio)sensing.Biosensors · 2026Review
- The transcriptome of dendritic cells redraws the boundaries between pathogenicity and commensalism in yeast.Microbial cell (Graz, Austria) · 2026Article
- Kawasaki disease and outdoor environmental stressors: a scoping review.The Lancet regional health. Western Pacific · 2026Review
- Immunoproteomic Identification ofJournal of proteome research · 2025Article
- Social Determinants of Health in Pediatric Asthma and Allergic Diseases: A Systematic Review.Epidemiologia (Basel, Switzerland) · 2025Review
- Early-Life Allergen Exposure and Its Influence on Risk of Atopic Disease.The journal of allergy and clinical immunology. In practice · 2025Review
- Home exposure to moisture and mold is associated with poorer asthma control in children: CHAMPIASTHMA study.The journal of allergy and clinical immunology. Global · 2025Article
- Allergen-induced activation of epithelial P2YThe Journal of allergy and clinical immunology · 2025Article
- Phylogenetic and ecological drivers of the avian lung mycobiome and its potentially pathogenic component.Communications biology · 2025Article
- The immune response of upper and lower airway epithelial cells to Aspergillus fumigatus and Candida albicans-derived β-glucan in Th17 type cytokine environment.Archives of microbiology · 2025Article
- Clinical Significance of Combined Detection of CCL22 and IL-1 as Potential New Bronchial Inflammatory Mediators in Children's Asthma.Immunity, inflammation and disease · 2024Article
- Fungal primary and opportunistic pathogens: an ecological perspective.FEMS microbiology reviews · 2024Review
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- Impact of Zinc Oxide on the Development ofCurrent issues in molecular biology · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fungi are ubiquitous outdoors and indoors. Exposure, sensitization, or both to fungi are strongly associated with development of asthma and allergic airway diseases. Furthermore, global climate change will likely increase the prevalence of fungi and enhance their antigenicity. Major progress has been made during the past several years regarding our understanding of antifungal immunity. Fungi contain cell-wall molecules, such as β-glucan and chitin, and secrete biologically active proteases and glycosidases. Airway epithelial cells and innate immune cells, such as dendritic cells, are equipped with cell-surface molecules that react to these fungal products, resulting in production of cytokines and proinflammatory mediators. As a result, the adaptive arm of antifungal immunity, including T
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.