ArticleThe journal of nutrition, health & aging2018
Muscle, Health and Costs: A Glance at their Relationship.
Article in The journal of nutrition, health & aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04584944 (Appendicular Skeletal Muscle Mass Adult Reference Measurements in Greek Population), which is not on this map. Cited by 97 papers, 7 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Appendicular Skeletal Muscle Mass Adult Reference Measurements in Greek Population
Who cites it
97 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Outcomes in clinical trials on sarcopenia: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2026Pooled it
- Traditional Chinese exercises on muscle strength, muscle mass, and physical function in older adults with sarcopenia: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.Frontiers in cellular and infection microbiology · 2025Pooled it
- The devastating trio of sarcopenia, frailty, and COVID-19 - A systematic review and meta-analysis.Clinical nutrition ESPEN · 2022Pooled it
- Can conditions of skeletal muscle loss be improved by combining exercise with anabolic-androgenic steroids? A systematic review and meta-analysis of testosterone-based interventions.Reviews in endocrine & metabolic disorders · 2021Pooled it
- Nutritional Intervention to Prevent the Functional Decline in Community-Dwelling Older Adults: A Systematic Review.Nutrients · 2020Pooled it
- Pooled it
- Effect of calcifediol and cholecalciferol on muscle function in postmenopausal women: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Trial
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- Creatinine muscle index in UK Biobank: comparison with MRI and associations with frailty and mortality.Clinical kidney journal · 2026Article
- Randomized, double-blind, placebo-controlled trial of fecal microbiota transplantation from young physically active donors to promote resilient aging: clinical trial protocol (ARMOR study).BMC geriatrics · 2026Article
- Enablers and barriers toward home-based resistance exercise among older adults who completed a structured program: qualitative study using reflexive thematic analysis.BMC geriatrics · 2026Article
- Bridging assessment, biomarkers, and interventions: progress in muscle health research.Frontiers in rehabilitation sciences · 2026Article
- A Systematic Review of Digital Health for Non-older Adults with Risk of Sarcopenia.Progress in rehabilitation medicine · 2026Review
- Identifying risk factors for sarcopenia using machine learning: insights from multimodal data.European geriatric medicine · 2025Article
- Physical function versus cognitive status: Which better predicts independence in basic activities among long-lived cognitively preserved older adults.Australasian journal on ageing · 2025Article
- Optimizing sarcopenia screening in type 2 diabetes mellitus: A ROC curve evaluation of the SARC-F and the SARC-CalF.Osteoporosis and sarcopenia · 2025Article
- Nutrition Focused Physical Examination Components Specific to Older Adults: A Modified Delphi Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Article
- The Effects of Pulsed Electromagnetic Field (PEMF) on Muscular Strength, Functional Performance and Depressive Symptoms in Elderly Adults with Sarcopenia: A Short-Term Intervention.Life (Basel, Switzerland) · 2025Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the association between muscle parameters (mass, strength, physical performance) and activities of daily living (ADL), quality of life (QoL), and health care costs.
designCross-sectional Maastricht Sarcopenia Study (MaSS).
settingCommunity-dwelling, assisted-living, residential living facility.
participants227 adults aged 65 and older. MEASUREMENTS: Muscle mass, hand grip strength and physical performance were assessed by bio-electrical impedance, JAMAR dynamometer and the Short Physical Performance Battery, respectively. Health outcomes were measured by the Groningen Activity Restriction Scale (disability in ADL) and the EQ-5D-5L (QoL). Health care costs were calculated based on health care use in the past three months.
resultsMuscle strength and physical performance showed a strong correlation with ADL, QoL, and health care costs (P<.01); for muscle mass no significant correlations were observed. Regression analyses showed that higher gait speed (OR 0.06, 95%CI 0.01-0.55) was associated with a lower probability of ADL disability. Furthermore, slower chair stand (OR 1.23, 95%CI 1.08-1.42), and more comorbidities (OR 1.58, 95%CI 1.23-2.02) were explanatory factors for higher ADL disability. Explanatory factors for QoL and costs were: more disability in ADL (OR 1.26, 95%CI 1.12-1.41 for QoL; B = 0.09, P<.01 for costs) and more comorbidities (OR 1.44, 95%CI 1.14-1.82 for QoL; B = 0.35, P<.01 for costs).
conclusionLower gait speed and chair stand were potential drivers of disability in ADL. Disability in ADL and comorbidities were associated with QoL and health care costs in community-dwelling older adults. Improving physical performance may be a valuable target for future intervention and research to impact health burden and costs.
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Registered trials
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