Evidence map›Paper›PMID 30080137›Full record

ArticleeLife2018

Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles.

Garrett A Greenan, Bettina Keszthelyi, Ronald D Vale, David A Agard

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Garrett A GreenanDepartment of Biochemistry and Biophysics, University of California, San Francisco, United States.ORCID http://orcid.org/0000-0002-9045-7666
Bettina KeszthelyiDepartment of Biochemistry and Biophysics, University of California, San Francisco, United States.
Ronald D ValeDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, United States.ORCID https://orcid.org/0000-0003-3460-2758
David A AgardDepartment of Biochemistry and Biophysics, University of California, San Francisco, United States.ORCID http://orcid.org/0000-0003-3512-695X

Funding

Microtubule Nucleation: Structure & MechanismR01GM031627 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AGARD, DAVID A. · 1985 to 2016
$6.1M
Structure & Mechanism: microtubule nucleation, centrosomes, phage cytoskeletonR35GM118099 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AGARD, DAVID A. · 2016 to 2022
$3.6M
Regulation of Microtubule-Based MotilityR35GM118106 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VALE, RONALD D · 2016 to 2020
$1.7M
Howard Hughes Medical InstituteNIGMS NIH HHS GM031627NIGMS NIH HHS GM118099NIGMS NIH HHS GM118106NIGMS NIH HHS R01 GM031627NIGMS NIH HHS R35 GM118099NIGMS NIH HHS R35 GM118106
6 · The paper itself

Abstract

Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia. While the structure of the cilium is being defined at increasing resolution, centriolar structure remains poorly understood. Here, we used electron cryo-tomography to determine the structure of mammalian (triplet) and

Indexed as

Cryoelectron MicroscopyAnimalsCentriolesCHO CellsCiliaCricetulusDrosophila melanogasterElectron Microscope TomographyMicrotubulesOlfactory Receptor Neuronscell biologycentriolecentrosomecryo-electron tomographyD. melanogastermicrotubule

Identifiers

PMID30080137
PMCPMC6110610

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.