ArticleDevelopment and psychopathology2019
Stress, Psychological Resources, and HPA and Inflammatory Reactivity During Late Adolescence.
Article in Development and psychopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Ginseng Bioactive Components as Gut-Brain Axis-Targeted Modulators: Therapeutic Potential and Mechanisms in Multifactorial Diseases.Nutrients · 2026Pooled it
- The Link Between Positive and Negative Parenting Behaviors and Child Inflammation: A Systematic Review.Child psychiatry and human development · 2023Pooled it
- Age-dependent associations of psychological and family factors on systemic inflammation in childhood acute lymphoblastic leukemia survivors.Journal of cancer survivorship : research and practice · 2026Article
- Emotion regulation as a protective factor in the association between stress and inflammation in older adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- How community connection, homophobia, and racism shape gene expression in sexual minority men with and without HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- The effects of a 12-week moderate-intensity continuous training intervention on depression, anxiety, and stress in sedentary female college students: a focus on negative emotion regulation.Frontiers in psychology · 2025Article
- Immune and neural response to acute social stress in adolescent humans and rodents.Translational psychiatry · 2024Article
- Increased C-Reactive Protein in Patients with Post-Stroke Depression: A Meta-analysis of Cohort Study.Alpha psychiatry · 2024Review
- Life stressors and immune aging: Protective effects of cognitive reappraisal.Brain, behavior, and immunity · 2023Article
- Resting respiratory sinus arrhythmia is related to emotion reactivity to social-evaluative stress.Journal of affective disorders · 2023Article
- A pathway to greater meaning in life and well-being for senior executives beset by anti-meaning.Frontiers in psychology · 2023Article
- Psychological Resources as a Buffer Between Racial/Ethnic and SES-based Discrimination and Adolescents' Academic Well-being.Journal of youth and adolescence · 2022Article
- Academic Stress and Mental Well-Being in College Students: Correlations, Affected Groups, and COVID-19.Frontiers in psychology · 2022Article
- Social media use and systemic inflammation: The moderating role of self-esteem.Brain, behavior, & immunity - health · 2021Article
- The contribution of dispositional optimism to understanding insomnia symptomatology: Findings from a cross-sectional population study in Austria.Journal of sleep research · 2021Article
- Rethinking Concepts and Categories for Understanding the Neurodevelopmental Effects of Childhood Adversity.Perspectives on psychological science : a journal of the Association for Psychological Science · 2021Article
- Saliva cortisol, melatonin levels and circadian rhythm alterations in Chinese primary school children with dyslexia.Medicine · 2020Article
- Subjective social status and stress responsivity in late adolescence.Stress (Amsterdam, Netherlands) · 2020Article
- Depressive symptoms and immune transcriptional profiles in late adolescents.Brain, behavior, and immunity · 2019Article
- Daily interpersonal stress, sleep duration, and gene regulation during late adolescence.Psychoneuroendocrinology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Psychosocial stress during childhood and adolescence is associated with alterations in the hypothalamic-pituitary-adrenal (HPA) axis and with heightened inflammation, both of which are implicated in poor health; however, factors that may protect against these effects relatively early in life are not well understood. Thus, we examined whether psychosocial resources protect against stress-related alterations in the HPA axis and heightened inflammation in a sample of 91 late adolescents. Participants completed measures of various stressors (major life events, daily interpersonal stress, early adversity), and psychosocial resources (mastery, optimism, self-esteem, and positive reappraisal). They also completed the Trier Social Stress Test and provided saliva and blood samples for the assessment of cortisol and interleukin-6 reactivity. Each of the stressors was associated with lower cortisol reactivity. Additionally, associations with major life events and daily stress were moderated by psychological resources, such that more life events and daily stress were associated with decreased HPA reactivity among adolescents with lower levels of psychological resources, but not among those with higher levels of psychological resources. This pattern of findings was observed only for cortisol reactivity and not for interleukin-6 reactivity. Findings suggest that psychological resources may counteract the effects of certain adversity-related decreases in cortisol reactivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.