ReviewThe world journal of men's health2019
Type 2 Diabetes and Testosterone Therapy.
Review in The world journal of men's health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- The mediating role of testosterone in the relationship between body fat percentage and diabetes mellitus risk.Frontiers in endocrinology · 2026Article
- Insulin resistance and cancer: molecular links and clinical perspectives.Molecular and cellular biochemistry · 2025Review
- The Impact of the SMOTE Method on Machine Learning and Ensemble Learning Performance Results in Addressing Class Imbalance in Data Used for Predicting Total Testosterone Deficiency in Type 2 Diabetes Patients.Diagnostics (Basel, Switzerland) · 2024Article
- Higher testosterone is associated with open-angle glaucoma in women: a genetic predisposition?Biology of sex differences · 2023Article
- Association of Body Composition with Pulmonary Function in Ningxia: The China Northwest Cohort.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Prevalence and determinants of low testosterone levels in men with type 2 diabetes mellitus; a case-control study in a district hospital in Ghana.PLOS global public health · 2021Article
- Testosterone treatment improves liver function and reduces cardiovascular risk: A long-term prospective study.Arab journal of urology · 2021Article
- Sex and ethnic differences in the cardiovascular complications of type 2 diabetes.Therapeutic advances in endocrinology and metabolism · 2021Review
- Prevalence of Low Testosterone According to Health Behavior in Older Adults Men.Healthcare (Basel, Switzerland) · 2020Article
- Testosterone deficiency syndrome among males with type 2 diabetes mellitus in East Malaysia.Nagoya journal of medical science · 2020Article
- Stem Leydig Cells in the Adult Testis: Characterization, Regulation and Potential Applications.Endocrine reviews · 2020Review
- Sexual dysfunction and mental health in patients with multiple sclerosis and epilepsy.BMC neurology · 2020Article
- The Role of Diet and Weight Loss in Improving Secondary Hypogonadism in Men with Obesity with or without Type 2 Diabetes Mellitus.Nutrients · 2019Article
- Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells.Reproductive biology and endocrinology : RB&E · 2019Article
- Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study.BMJ (Clinical research ed.) · 2019Article
- The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism.Journal of clinical medicine · 2019Review
- Do Androgens Modulate the Pathophysiological Pathways of Inflammation? Appraising the Contemporary Evidence.Journal of clinical medicine · 2018Review
- Effects of Testosterone Treatment on Quality of Life in Patients With Chronic Kidney Disease.American journal of men's healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A third of men with type 2 diabetes (T2DM) have hypogonadotrophic hypogonadism (HH) and associated increased risk of cardiovascular and all-cause mortality. Men with HH are at increased risk of developing incident T2DM. We conducted MEDLINE, EMBASE, and COCHRANE reviews on T2DM, HH, testosterone deficiency, cardiovascular and all-cause mortality from May 2005 to October 2017, yielding 1,714 articles, 52 clinical trials and 32 randomized controlled trials (RCT). Studies with testosterone therapy suggest significant benefits in sexual function, quality of life, glycaemic control, anaemia, bone density, fat, and lean muscle mass. Meta-analyses of RCT, rather than providing clarification, have further confused the issue by including under-powered studies of inadequate duration, multiple regimes, some discontinued, and inbuilt bias in terms of studies included or excluded from analysis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.