Evidence map›Paper›PMID 30079439›Full record

ArticleOral and maxillofacial surgery2018

Oral hairy leukoplakia in healthy immunocompetent patients: a small case series.

Daire Shanahan, Rachel Cowie, Helen Rogers, Konrad Staines

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Oral and maxillofacial surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Oral Hairy Leukoplakia: A Rare Involvement in a Patient with Polycythemia Vera.International journal of hematology-oncology and stem cell research · 2025
    Article
  3. A rare case of hairy leukoplakia in a young immunocompetent patient.Journal of clinical and experimental dentistry · 2025
    Article
  4. Common white lesions of the oral cavity: Review of clinical presentations and management.Canadian family physician Medecin de famille canadien · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daire ShanahanDepartment of Oral Medicine, The University of Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, England. daire.shanahan@UHbristol.nhs.uk.ORCID http://orcid.org/0000-0002-6872-9397
Rachel CowieDepartment of Oral Medicine, The University of Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, England.
Helen RogersDepartment of Oral Medicine, The University of Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, England.
Konrad StainesDepartment of Oral Medicine, The University of Bristol Dental Hospital, Lower Maudlin Street, Bristol, BS1 2LY, England.
University Of Bristol Dental Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral hairy leukoplakia (OHL) is caused by the Epstein-Barr virus (EBV) and usually presents in patients with human immunodeficiency virus (HIV) infection and systemic immunosuppression. It is rarely seen in patients who are immunocompetent. It is clinically characterised as an asymptomatic, soft, white and corrugated lesion that cannot be scraped from the surface it adheres to.

methodsImmunocompetent patients with OHL attending Bristol Dental Hospital within the last 6 months were identified. EBV infection was demonstrated using EBV in situ hybridization. Clinical features and medical history were determined by reviewing medical records. CASE REPORT: Four cases of OHL in immunocompetent individuals were identified. All lesions were located on the lateral borders of the tongue. DISCUSSION: OHL should be considered as a differential diagnosis for white patches on the lateral borders of the tongue in apparently healthy immunocompetent patients, even when they do not have a typical corrugated appearance. OHL should no longer be regarded as pathognomonic for HIV infection or systemic immunosuppression.

Indexed as

AdolescentAdultAgedDiagnosis, DifferentialEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansIn Situ HybridizationLeukoplakia, HairyMaleEpstein-Barr virusHIV-negative patientsImmunocompetentOral hairy leukoplakia

Identifiers

PMID30079439
OpenAlexW2887683915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.