Evidence map›Paper›PMID 30079382›Full record

ArticleCurrent opinion in toxicology2018

Oxidative Stress from Environmental Exposures.

James M Samet, Phillip A Wages

Abstract read
In one paragraph

Article in Current opinion in toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Review
  3. iScience · 2026
    Article
  4. Review
  5. Review
  6. Dynamic redox monitoring in differentiated human neuroblastoma models of Parkinson's disease.Redox report : communications in free radical research · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Ferroptosis in Toxicology: Present and Future.International journal of molecular sciences · 2025
    Review
  11. Article
  12. Oxidative Stress and DNA Damage at Telomeres.Cold Spring Harbor perspectives in biology · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. MicroRNAs as Regulators of Radiation-Induced Oxidative Stress.Current issues in molecular biology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James M SametEnvironmental Public Health Division, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC 27707.
Phillip A WagesDepartment of Chemistry, Vanderbilt University, Nashville, TN 49795.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Oxidative stress is arguably the most common mechanism in the toxicology of environmental agents, unifying the action of broad classes of physichochemically disparate environmental pollutants, including oxidant gases, organic compounds, particulate surfaces, and metal ions. As advances in redox biology identify previously unrecognized targets for disruption by exposure to xenobiotics, redox toxicology has emerged as a new field of investigation. Environmental contaminants can induce oxidative stress on cells through mechanisms that are direct, indirect or involve the disruption of metabolic or bioenergetic processes that are regulated by thiol redox switches. Live-cell imaging has proven to be a powerful approach to the study of environmental oxidative stress. Cells are equipped with multiple complementary energy-dependent systems for maintaining redox homeostasis in the face of environmental oxidative stress.

Indexed as

environmental exposureglutathionelive cell imagingOxidative stressperoxiredoxinthiolsthioredoxintoxicologyxenobiotic

Identifiers

PMID30079382
PMCPMC6069528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.