Evidence map›Paper›PMID 30079211›Full record

ArticleChemical science2018

Guiding protein delivery into live cells using DNA-programmed membrane fusion.

Lele Sun, Yanjing Gao, Yaoguang Wang, Qin Wei, Jiye Shi, Nan Chen, Di Li, Chunhai Fan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 80 citations in OpenAlex.

  1. Membrane-Associated Biomolecules for Synthetic Cell Signalling.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Computational design of membrane fusion proteins.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Review
  5. The strategies and advances of mRNA translation booster.Asian journal of pharmaceutical sciences · 2025
    Review
  6. Review
  7. DNA-programmed cell assembly: from cells, tissues to organoids.Frontiers in bioengineering and biotechnology · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Lele SunDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.
Yanjing GaoDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.
Yaoguang WangKey Laboratory of Chemical Sensing & Analysis in Universities of Shandong , School of Chemistry and Chemical Engineering , University of Jinan , Jinan 250022 , China.ORCID 0000-0003-0635-331X
Qin WeiKey Laboratory of Chemical Sensing & Analysis in Universities of Shandong , School of Chemistry and Chemical Engineering , University of Jinan , Jinan 250022 , China.ORCID 0000-0002-3034-8046
Jiye ShiDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.
Nan ChenDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.
Di LiDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.ORCID 0000-0003-1674-0110
Chunhai FanDivision of Physical Biology & Bioimaging Centre , Shanghai Synchrotron Radiation Facility , Key Laboratory of Interfacial Physics and Technology , Shanghai Institute of Applied Physics , Chinese Academy of Sciences , Shanghai 201800 , China . Email: dli@chem.ecnu.edu.cn.ORCID 0000-0002-7171-7338
Chinese Academy of Sciences · CNUniversity of Jinan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracellular delivery of proteins provides a direct means to manipulate cell function and probe the intracellular environment. However, direct cytoplasmic delivery of proteins suffers from limited availability of efficient toolsets, and thus remains challenging in research and therapeutic applications. Natural biological cargo delivery processes, like SNARE (soluble

Identifiers

PMID30079211
PMCPMC6050539
OpenAlexW2808137381

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.