Evidence map›Paper›PMID 30079195›Full record

ArticleChemical science2018

The intramolecular hydrogen bonded-halogen bond: a new strategy for preorganization and enhanced binding.

Asia Marie S Riel, Daniel A Decato, Jiyu Sun, Casey J Massena, Morly J Jessop, Orion B Berryman

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 98 citations in OpenAlex.

  1. Article
  2. Discovery of conformation constrained tetracyclic compounds as potent chitinaseJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  3. Article
  4. Illuminating the Performance of Electron Withdrawing Groups in Halogen Bonding.Chemphyschem : a European journal of chemical physics and physical chemistry · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  13. Article
  14. The Influence of Secondary Interactions on the [N-I-N]Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Enhancement of Ion Pairing of Sr(II) and Ba(II) Salts by a Tritopic Ion-Pair Receptor in Solution.Chemphyschem : a European journal of chemical physics and physical chemistry · 2020
    Article
  19. Article
  20. Helical Anion Foldamers in Solution.Chemical reviews · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Asia Marie S RielUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.
Daniel A DecatoUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.
Jiyu SunUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.
Casey J MassenaUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.
Morly J JessopUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.
Orion B BerrymanUniversity of Montana , 32 Campus Drive , Missoula , MT , USA . Email: orion.berryman@umontana.edu.ORCID 0000-0002-0324-484X
Missoula County Public Schools · US

Funding

Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP20GM103546 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2012 to 2021
$19.2M
NIGMS NIH HHS P20 GM103546
6 · The paper itself

Abstract

Natural and synthetic molecules use weak noncovalent forces to preorganize structure and enable remarkable function. Herein, we introduce the intramolecular hydrogen bonded-halogen bond (HB-XB) as a novel method to preorganize halogen bonding (XBing) molecules, while generating a polarization-enhanced XB. Positioning a fluoroaniline between two iodopyridinium XB donors engendered intramolecular hydrogen bonding (HBing) to the electron-rich belt of both XB donors. NMR solution studies established the efficacy of the HB-XB. The receptor with HB-XBs (

Identifiers

PMID30079195
PMCPMC6050591
OpenAlexW4232295448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.