ArticleFrontiers in genetics2018
Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity.
Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research.American journal of human genetics · 2025Article
- Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies.Nature communications · 2023Article
- The Genetic Echo of the Tarim Mummies in Modern Central Asians.Molecular biology and evolution · 2022Article
- High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran.Scientific reports · 2020Article
- Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages.Cell communication and signaling : CCS · 2019Article
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Abstract
Supervised clustering or projection analysis is a staple technique in population genetic analysis. The utility of this technique depends critically on the reference panel. The most commonly used reference panel in the analysis of ancient DNA to date is based on the Human Origins array. We previously described a larger reference panel that captures more ancestries on the global level. Here, I reanalyzed DNA data from 279 ancient Eurasians using our reference panel. I found substantially more ancestral heterogeneity than has been reported. Reanalysis provides evidence against a resurgence of Western hunter-gatherer ancestry in the Middle to Late Neolithic and evidence for a common ancestor of farmers characterized by Western Asian ancestry, a transition of the spread of agriculture from demic to cultural diffusion, at least two migrations between the Pontic-Caspian steppes and Bronze Age Europe, and a sub-Saharan African component in Natufians that localizes to present-day southern Ethiopia.
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