ArticleJournal of laboratory physicians
Direct testing by VITEK
Article in Journal of laboratory physicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Evaluation of an adapted relative growth method by MALDI-TOF MS for rapid determination of the susceptibility ofMicrobiology spectrum · 2026Article
- Prophylactic and therapeutic efficacy of Acinetobacter phage RM_A1 against carbapenem-resistant Acinetobacter baumannii with no cytotoxicity to human skin cells.BMC microbiology · 2026Article
- Improved Utilisation and Quality of Blood Culture Services Following Operational Research in a Tertiary Hospital in Ghana.Tropical medicine and infectious disease · 2025Article
- Simple dual filter workflow for facilitating blood culture-free and sensitive detection of pathogenic bacteria from blood.Scientific reports · 2025Article
- Modification of the rapid antimicrobial susceptibility testing from blood culture protocol for a resource-limited setting.JAC-antimicrobial resistance · 2025Article
- Pioneering study of Egyptian Neem and Jojoba extracts with molecular docking combat hospital multidrug resistant bacteria.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- PathCrisp: an innovative molecular diagnostic tool for early detection of NDM-resistant infections.Scientific reports · 2025Article
- Evolving strategies in microbe identification-a comprehensive review of biochemical, MALDI-TOF MS and molecular testing methods.The Journal of antimicrobial chemotherapy · 2024Review
- Evaluation of the QMAC-dRAST System Version 2.5 for Rapid Antimicrobial Susceptibility Testing of Gram-Negative Bacteria From Positive Blood Culture Broth and Subcultured Colony Isolates.Journal of clinical laboratory analysis · 2024Article
- Moving microcapillary antibiotic susceptibility testing (mcAST) towards the clinic: unravelling kinetics of detection of uropathogenicSensors & diagnostics · 2023Article
- Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing.Antibiotics (Basel, Switzerland) · 2022Review
- Antimicrobial susceptibility testing for Gram positive cocci towards vancomycin using scanning electron microscopy.Current research in microbial sciences · 2022Article
- Article
- Comparison of novel approaches for expedited pathogen identification and antimicrobial susceptibility testing against routine blood culture diagnostics.Letters in applied microbiology · 2021Article
- Rapid Methods for Antimicrobial Resistance Diagnostics.Antibiotics (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextBloodstream infections pose a major health-care burden worldwide. Routine microbiological methods are time-consuming, thereby delaying appropriate treatment.
aimsThe aim of this study is to evaluate the method of direct testing of identification (ID) and antimicrobial susceptibility testing (AST) of positive blood culture bottles by VITEK SETTINGS AND
designThis was a prospective study at a tertiary level hospital. SUBJECTS AND
methodsOne hundred positive BACTEC blood culture bottles with monomicrobial Gram-negative organisms on microscopy were tested in parallel by direct ID/AST as well as conventional method. Results obtained by two methods were compared in terms of ID/AST and turnaround time (TAT).
resultsOf the 100 isolates tested, only one was misidentified by the direct method and there was no unidentified isolate. The AST results demonstrated 99.74% categorical and 99.65% essential agreement. Of 1144 organism-antibiotic combinations, there were 0.44% major error, no very major error, or minor error observed.
conclusionsWhile conventional method is the gold standard, the direct ID/AST methods have demonstrated that it can be successfully utilized to decrease TAT to the final results by 18-24 h, without sacrificing test accuracy. This technique will help to tailor antimicrobial therapy, thereby reducing patient morbidity, mortality, and antibiotic resistance, as well.
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