Evidence map›Paper›PMID 30078066›Full record

SynthesisSports medicine (Auckland, N.Z.)2018

The Acute Metabolic and Vascular Impact of Interrupting Prolonged Sitting: A Systematic Review and Meta-Analysis.

Travis J Saunders, Hayden F Atkinson, Jamie Burr, Brittany MacEwen, C Murray Skeaff, Meredith C Peddie

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06592209 (Body Electric), which is not on this map. Cited by 82 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 13 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06592209 nacompletednot on this mapstarted 2023, after this paper: background citation

Body Electric: a Pragmatic Trial Evaluating Movement Breaks As a Public Health Strategy to Mitigate the Harms of Prolonged Sedentary Behavior

TypeinterventionalSponsorColumbia UniversityRan2023 to 2023Enrolled20,217ConditionsSedentary BehaviorArmsSedentary Breaks
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 13 syntheses or guidelines pooled it, 179 citations in OpenAlex.

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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Travis J SaundersDepartment of Applied Human Sciences, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE, C1A 4P3, Canada. trsaunders@upei.ca.
Hayden F AtkinsonGraduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences, School of Physical Therapy, University of Western Ontario, London, ON, Canada.
Jamie BurrDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Brittany MacEwenDepartment of Applied Human Sciences, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE, C1A 4P3, Canada.
C Murray SkeaffDepartment of Human Nutrition, University of Otago, Otago, New Zealand.
Meredith C PeddieDepartment of Human Nutrition, University of Otago, Otago, New Zealand.
University of Otago · NZUniversity of Prince Edward Island · CAFowler Kennedy Sport Medicine Clinic · CAUniversity of Guelph · CA

Funding

National Heart Foundation of New Zealand (NZ) 1745
6 · The paper itself

Abstract

objectiveThe aim was to conduct a systematic review and meta-analysis analyzing the impact of up to 24 h of prolonged sitting on postprandial glucose, insulin and triglyceride responses, blood pressure and vascular function, in comparison to sitting interrupted with light- to moderate-intensity physical activity.

methodsTo be included, studies had to examine the impact of prolonged sitting lasting < 24 h in apparently healthy males or females of any age. Studies were identified from searches of the MEDLINE, CINAHL and SportDISCUS databases on July 6, 2016. Study quality was assessed using the Downs and Black Checklist; publication bias was assessed via funnel plot.

resultsForty-four studies met the inclusion criteria for the systematic review; of these, 20 were included in the meta-analysis, which compared prolonged sitting to the effects of interrupting sitting with regular activity breaks on postprandial glucose, insulin and triglycerides. When compared to prolonged sitting, regular activity breaks lowered postprandial glucose (d = - 0.36, 95% confidence interval [CI] - 0.50 to - 0.21) and insulin (d = - 0.37, 95% CI - 0.53 to - 0.20), but not triglyceride responses (d = 0.06, 95% CI - 0.15 to 0.26). Subgroup analyses indicated reductions in postprandial triglyceride responses only occurred 12-16 h after the intervention. The magnitude of the reductions in glucose, insulin or triglyceride response was not modified by the intensity of the activity breaks, the macronutrient composition of the test meal, or the age or body mass index of participants.

conclusionProlonged sitting results in moderate elevations in postprandial glucose and insulin responses when compared to sitting interrupted with activity breaks. PROSPERO ID: CRD42015020907.

Indexed as

Sedentary BehaviorSitting PositionBlood GlucoseBlood PressureHumansInsulinMealsPostprandial PeriodRandomized Controlled Trials as TopicTriglyceridesVascular StiffnessBlood GlucoseInsulinTriglycerides

Identifiers

PMID30078066
OpenAlexW2887266455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.