Evidence map›Paper›PMID 30077502›Full record

ArticleAnales de pediatria2019

[Previous or coincident infections with suspected Kawasaki disease. Should we change our approach?]

Elisa Fernández-Cooke, Ana Barrios Tascón, Jordi Antón-López, Carlos Daniel Grasa Lozano, Judith Sánchez-Manubens, Cristina Calvo, en representación del Grupo de trabajo para el estudio de la enfermedad de Kawasaki (KAWA-RACE)

Open access · diamondAbstract read
In one paragraph

Article in Anales de pediatria, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Elisa Fernández-CookeServicio de Pediatría, Hospital 12 de Octubre, Madrid, España. Electronic address: elisafcooke@gmail.com.
Ana Barrios TascónServicio de Pediatría, Hospital Infanta Sofía, San Sebastián de los Reyes (Madrid), España.
Jordi Antón-LópezServicio de Pediatría, Hospital Sant Joan de Déu, Esplugues de Llobregat (Barcelona), España.
Carlos Daniel Grasa LozanoServicio de Pediatría, Hospital 12 de Octubre, Madrid, España.
Judith Sánchez-ManubensServicio de Pediatría, Hospital Sant Joan de Déu, Esplugues de Llobregat (Barcelona), España.
Cristina CalvoServicio de Pediatría, Hospital Universitario La Paz, Madrid, España.
en representación del Grupo de trabajo para el estudio de la enfermedad de Kawasaki (KAWA-RACE)
Hospital Sant Joan de Déu Barcelona · ESHospital Universitario 12 De Octubre · ESHospital Universitario Infanta Sofía · ESHospital Universitario La Paz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKawasaki disease (KD) is a multisystem vasculitis associated with coronary artery abnormalities. Infections could be a trigger of the inflammation. The main aim of this study was to describe the presence of infections in children with KD, and to analyse the clinical characteristics and the presence of coronary abnormalities in these cases. PATIENTS AND

methodsA retrospective study was performed within the Kawasaki Diseases Network (KAWA-RACE (2011-2016). An analysis was performed that included patients with positive microbiological findings (PMF) during the acute phase, as well as those with a previous recent infection (PRI) during the 4 weeks preceding KD diagnosis.

resultsThe study included total of 621 children with KD, with PMF being found in 101 (16.3%) patients, and a PRI in 107 (17.2%). Significantly less echocardiographic abnormalities were found in the in the group with a PRI, when compared to those without a PRI (23 vs. 35%, P=.01) and also a lower proportion of overall coronary artery lesions (16 vs. 25%, P=.054). No significant differences were found in the proportion of aneurysms in either of these groups (PRI or PMF) when compared to those without infection.

conclusionsIn the present study, no differences were found in the incidence of coronary aneurysms in either of the groups, with or without PRI or PMF. Therefore, if KD is suspected, appropriate treatment should be started despite having a confirmed infection.

Indexed as

Child, PreschoolCoronary AneurysmFemaleHumansIncidenceInfantInfectionsMaleMucocutaneous Lymph Node SyndromeRetrospective StudiesAneurismas coronariosCoronary aneurysmEnfermedad de KawasakiKawasaki diseaseVasculitis

Identifiers

PMID30077502
PMCPMC7105073
OpenAlexW2887122540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.