ArticleThe American journal of cardiology2018
Serial Studies in Subclinical Atherosclerosis During Menopausal Transition (from the Study of Women's Health Across the Nation).
Article in The American journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Metabolic Changes of Perimenopause and Nutritional Advice.Current nutrition reports · 2026Review
- Exploring Glycocalyx shedding markers: A comparative analysis of plasma markers among premenopausal and postmenopausal women.Physiological reports · 2026Article
- Obesity and female reproductive health in Asian population.Obesity pillars · 2026Review
- Physical activity moderates the relationship between hot flashes and arterial wave reflection in perimenopausal females.Physiological reports · 2026Article
- Review
- Decreased Bone Mineral Density Is Associated with Subclinical Atherosclerosis in Asymptomatic Non-Diabetic Postmenopausal Women.Journal of clinical medicine · 2025Article
- Better Late Than Early? The Role of the Vascular Endothelium in Late-Onset Menopause.Circulation research · 2025Article
- Predictors of subclinical atherosclerosis in asymptomatic healthy non-diabetic postmenopausal women.Clinical physiology and functional imaging · 2025Article
- Construction and Comparison of Machine Learning-Based Risk Prediction Models for Major Adverse Cardiovascular Events in Perimenopausal Women.International journal of general medicine · 2025Article
- Article
- Characterizing vascular and hormonal changes in women across the life span: a cross-sectional analysis.American journal of physiology. Heart and circulatory physiology · 2024Article
- Metabolic benefits afforded by estradiol and testosterone in both sexes: clinical considerations.The Journal of clinical investigation · 2024Review
- Mechanism of Action of NvZhen ErXian HeJi in Ovariectomized Rats with Myocardial Infarction based on Network Pharmacology.Current pharmaceutical design · 2024Article
- Age-associated increases in middle cerebral artery pulsatility differ between men and women.American journal of physiology. Heart and circulatory physiology · 2023Article
- Pregnancy and Reproductive Risk Factors for Cardiovascular Disease in Women.Circulation research · 2022Review
- Roles of Hormone Replacement Therapy and Menopause on Osteoarthritis and Cardiovascular Disease Outcomes: A Narrative Review.Frontiers in rehabilitation sciences · 2022Review
- Menopausal Vasomotor Symptoms and Risk of Incident Cardiovascular Disease Events in SWAN.Journal of the American Heart Association · 2021 · on this mapArticle
- A multi-component, community-engaged intervention to reduce cardiovascular disease risk in perimenopausal Latinas: pilot study protocol.Pilot and feasibility studies · 2021Article
- Life-Course Reproductive History and Cardiovascular Risk Profile in Late Mid-Life: The CARDIA Study.Journal of the American Heart Association · 2020Article
- Arterial Stiffness Accelerates Within 1 Year of the Final Menstrual Period: The SWAN Heart Study.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
Cardiovascular disease risk increases in women after the menopausal transition; why this inflection point occurs remains uncertain. We aimed to characterize the influence of menopause on vascular aging by prospective assessment of change in indexes of subclinical atherosclerosis across the menopausal transition. We evaluated 411 healthy women from SWAN Heart, an ancillary study of SWAN (Study of Women's Health Across the Nation), for subclinical atherosclerosis at baseline and again after an average of 2.3 years. Carotid intima-media thickness and aortic pulse wave velocity were measured by ultrasound. Coronary artery calcium scores were obtained by computed tomography. Women were grouped by menopausal status as premenopausal, postmenopausal, or having undergone the transition during follow-up. Analyses of changes were adjusted for age at baseline and time between scans. Mean age at baseline was 51 ± 3 years; 93 (23%) subjects transitioned to menopause (Pre-Post), 147 (36%) remained premenopausal (Pre-Pre), while 171 (41%) were postmenopausal at baseline (Post-Post). Blood pressure readings did not differ between groups with similar increase noted in carotid intima-media thickness and log coronary artery calcium + 1 from baseline to follow-up. Change in aortic pulse wave velocity from baseline to follow-up was higher in Pre-Post (121 ± 23 cm/s) compared with Pre-Pre (38 ± 250 cm/s, p = 0.029) and Post-Post (41 ± 228 cm/s, p = 0.045). In conclusion, changes in aortic stiffness were more sensitive measures of perimenopausal vascular aging than morphologic indexes of subclinical atherosclerosis in women undergoing the menopausal transition. Serial assessment of such changes could potentially elucidate mechanisms of disease and identify women to target for aggressive lifestyle risk factor modification.
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