ReviewCurrent opinion in chemical biology2018
A new era for electron bifurcation.
Review in Current opinion in chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed.
- Molecular strategies for flux control in an electron bifurcation protein.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026Article
- pK Values of the Cofactor Tune the Redox Regime of Flavoenzymes.Life (Basel, Switzerland) · 2026Article
- Asymmetric Reduction of Unactivated Alkenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Lessons, connections, hypotheses and predictions from protein film electrochemistry.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026Review
- From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026Review
- Design of Light Driven Hole Bifurcating Proteins.ACS central science · 2025Article
- Dissecting Bioelectrical Networks in Photosynthetic Membranes with Electrochemistry.Journal of the American Chemical Society · 2025Article
- A [FeFe] Hydrogenase-Rubrerythrin Chimeric Enzyme Functions to Couple HJournal of the American Chemical Society · 2025Article
- Cryo-EM reveals a composite flavobicluster electron bifurcation site in the Bfu family member NfnABC.Communications biology · 2025Article
- Nitrogen-Fixing Gamma ProteobacteriaMicroorganisms · 2024Review
- Correlating Conformational Equilibria with Catalysis in the Electron Bifurcating EtfABCX ofBiochemistry · 2024Article
- Structures and Electron Transport Paths in the Four Families of Flavin-Based Electron Bifurcation Enzymes.Sub-cellular biochemistry · 2024Review
- Rapid-reaction kinetics of the bifurcating NADThe Journal of biological chemistry · 2023Article
- Mechanisms for Generating Low Potential Electrons across the Metabolic Diversity of Nitrogen-Fixing Bacteria.Applied and environmental microbiology · 2023Review
- Correlated particle transport enables biological free energy transduction.Biophysical journal · 2023Article
- Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC.Journal of the American Chemical Society · 2023Article
- Is biofilm formation intrinsic to the origin of life?Environmental microbiology · 2023Article
- Site-Differentiated Iron-Sulfur Cluster Ligation Affects Flavin-Based Electron Bifurcation Activity.Metabolites · 2022Article
- Tungsten Enzyme Using Hydrogen as an Electron Donor to Reduce Carboxylic Acids and NADACS catalysis · 2022Article
- An uncharacteristically low-potential flavin governs the energy landscape of electron bifurcation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
Electron bifurcation, or the coupling of exergonic and endergonic oxidation-reduction reactions, was discovered by Peter Mitchell and provides an elegant mechanism to rationalize and understand the logic that underpins the Q cycle of the respiratory chain. Thought to be a unique reaction of respiratory complex III for nearly 40 years, about a decade ago Wolfgang Buckel and Rudolf Thauer discovered that flavin-based electron bifurcation is also an important component of anaerobic microbial metabolism. Their discovery spawned a surge of research activity, providing a basis to understand flavin-based bifurcation, forging fundamental parallels with Mitchell's Q cycle and leading to the proposal of metal-based bifurcating enzymes. New insights into the mechanism of electron bifurcation provide a foundation to establish the unifying principles and essential elements of this fascinating biochemical phenomenon.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.