Evidence map›Paper›PMID 30076466›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2018

Efficient copper-based DNA cleavers from carboxylate benzimidazole ligands.

Víctor A Barrera-Guzmán, Edgar O Rodríguez-Hernández, Naytzé Ortíz-Pastrana, Ricardo Domínguez-González, Ana B Caballero, Patrick Gamez, Norah Barba-Behrens

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Anti-toxoplasma activity and DNA-binding of copper(II) and zinc(II) coordination compounds with 5-nitroimidazole-based ligands.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  2. DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  3. Alison Butler: papers in celebration of her 2018 ACS Alfred Bader Award in Bioorganic or Bioinorganic Chemistry.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Víctor A Barrera-GuzmánDepartamento de Química Inorgánica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, 04510, Mexico City, Mexico.
Edgar O Rodríguez-HernándezDepartamento de Química Inorgánica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, 04510, Mexico City, Mexico.
Naytzé Ortíz-PastranaDepartamento de Química, Cinvestav, A. P. 14-740, 07000, Mexico City, Mexico.
Ricardo Domínguez-GonzálezFacultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, 04510, Mexico City, Mexico.
Ana B CaballeroDepartament de Química Inorgánica y Orgánica, Universitat de Barcelona, Martí I Franqués 1-11, 08028, Barcelona, Spain.
Patrick GamezDepartament de Química Inorgánica y Orgánica, Universitat de Barcelona, Martí I Franqués 1-11, 08028, Barcelona, Spain. patrick.gamez@qi.ub.es.
Norah Barba-BehrensDepartamento de Química Inorgánica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, 04510, Mexico City, Mexico. norah@unam.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four copper(II) coordination compounds from 2-benzimidazole propionic acid (Hbzpr) and 4-(benzimidazol-2-yl)-3-thiobutanoic acid (Hbztb) were synthesized and fully characterized by elemental analyses, electronic spectroscopy, FT-IR and mass spectrometry. The molecular structure for the four complexes was confirmed by single-crystal X-ray crystallography. The DNA-interacting properties of the two trinuclear and two mononuclear compounds were investigated using different spectroscopic techniques including absorption titration experiments, fluorescence spectroscopy and circular dichroism spectroscopy. Trinuclear [Cu

Indexed as

BenzimidazolesCoordination ComplexesCopperCrystallography, X-RayDNADNA CleavageLigandsModels, MolecularMolecular StructurePlasmidsbenzimidazoleBenzimidazolesCoordination ComplexesCopperDNALigands2-Carboxylate benzimidazolesCopper(II) complexesct-DNADNA-cleaving propertiespBr322 DNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.