Observational studyWorld journal of urology2019
Diagnostic accuracy of third-generation dual-source dual-energy CT: a prospective trial and protocol for clinical implementation.
Observational study in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 32 citations in OpenAlex.
- Dual-source CT for medical dissolution of uric acid stones: a retrospective derivation and prospective validation study.European journal of medical research · 2026Article
- The Composition Analysis of Renal Staghorn Calculi and their Characteristics using Spectral CTCurrent medical imaging · 2025Article
- Demonstrating the Efficacy of Dual Energy Computer Tomography with Gemstone Spectral Imaging Software to Determine Mixed and Single Composition ex vivo Urolithiasis.Research and reports in urology · 2024Article
- Diagnostic performance and feasibility of dual-layer detector dual-energy CT for characterization of urinary stones in patients of different sizes.Abdominal radiology (New York) · 2024Article
- [Diagnostic values of urinary citrate for kidney stones in patients with primary gout].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- The characterization of in vivo urinary phospate stones by spectral CT.Urolithiasis · 2022Article
- The combination of mean and maximum Hounsfield Unit allows more accurate prediction of uric acid stones.Urolithiasis · 2022Article
- Clinical Low Dose Photon Counting CT for the Detection of Urolithiasis: Evaluation of Image Quality and Radiation Dose.Tomography (Ann Arbor, Mich.) · 2022Article
- Prevalence of Monosodium Urate (MSU) Deposits in Cadavers Detected by Dual-Energy Computed Tomography (DECT).Diagnostics (Basel, Switzerland) · 2022Article
- Revolution spectral CT for urinary stone with a single/mixed composition in vivo: a large sample analysis.World journal of urology · 2021Article
- Dual-Energy CT for Urinary Stone Evaluation.Current urology reports · 2020Review
- Pre-operative Percutaneous Nephrolithotripsy Characterisation of Kidney Stones with Second-Generation Dual-Source Dual-Energy Computed Tomography.The Malaysian journal of medical sciences : MJMS · 2020Article
- Dose independent characterization of renal stones by means of dual energy computed tomography and machine learning: an ex-vivo study.European radiology · 2020Article
- Changes in the Selected Antioxidant Defense Parameters in the Blood of Patients after High Resolution Computed Tomography.International journal of environmental research and public health · 2019Article
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8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeUric acid (UA) calculi can be referred to chemolitholysis rather than invasive treatment. Dual-energy computed tomography (DECT) may be able to distinguish between UA and non-UA (NUA) calculi. The aim of this study was to evaluate the validity of third-generation DECT for the first time and to investigate whether combining DECT with clinical parameters can increase its predictive accuracy. MATERIALS AND
methodsAll patients who presented to our emergency department between January 2015 and March 2017 with urinary stones were prospectively included in this observational study and underwent DECT with subsequent interventional stone removal. Stone composition was analyzed using infrared spectrometry as the gold standard. Predictive accuracy of DECT and clinical covariates was computed by assessing univariate and multivariate areas under the curve (AUCs).
resultsOf 84 patients with 144 urinary stones, 10 (11.9%) patients had UA stones according to infrared spectrometry, and the remaining stones were NUA or mixed stones. DECT had a positive predictive value of 100% and a negative predictive value of 98.5% for UA stones. The AUC for urine pH alone was 0.71 and 0.97 for DECT plus urine pH. No UA stones were found in patients with a urine pH above > 5.5. Mean DLP was 225.15 ± 128.60 mGy*cm and mean effective dose was 3.38 ± 1.93 mSv.
conclusionsDECT is a safe method for assigning patients to oral chemolitholysis. Clinical preselection of patients based on urinary pH (< 6.0) leads to a more liable use of DECT. Third-generation DECT needs significant lower radiation doses compared to previous generations.
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