Evidence map›Paper›PMID 30076380›Full record

ArticleScientific reports2018

Fire blight host-pathogen interaction: proteome profiles of Erwinia amylovora infecting apple rootstocks.

Michelle Holtappels, Jean-Paul Noben, Patrick Van Dijck, Roland Valcke

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. Biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Michelle HoltappelsMolecular and Physical Plant Physiology, Faculty of Sciences, Hasselt University, Diepenbeek, B-3590, Belgium.
Jean-Paul NobenSchool of Life Sciences, Biomedical Research Institute, Hasselt University and Transnational University Limburg, Hasselt, B-3590, Belgium.ORCID 0000-0003-3368-5686
Patrick Van DijckKU Leuven, Laboratory of Molecular Cell Biology VIB-KU Leuven, Center for Microbiology, Institute of Botany and Microbiology, KU Leuven, B-3001, Heverlee - Leuven, Belgium.ORCID 0000-0002-1542-897X
Roland ValckeMolecular and Physical Plant Physiology, Faculty of Sciences, Hasselt University, Diepenbeek, B-3590, Belgium. roland.valcke@uhasselt.be.
VIB-KU Leuven Center for Microbiology · BEHasselt University · BETransnational University Limburg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fire blight, caused by the enterobacterium Erwinia amylovora, is a destructive disease, which can affect most members of the Rosaceae family. Since no significant genomic differences have been found by others to explain differences in virulence, we used here a gel-based proteomic approach to elucidate mechanisms and key players that allow the pathogen to survive, grow and multiply inside its host. Therefore, two strains with proven difference in virulence were grown under controlled conditions in vitro as well as in planta (infected apple rootstocks). Proteomic analysis including 2DE and mass spectrometry revealed that proteins involved in transcription regulation were more abundant in the in planta condition for both strains. In addition, genes involved in RNA processing were upregulated in planta for the highly virulent strain PFB5. Moreover, the upregulation of structural components of the F

Indexed as

Host-Pathogen InteractionsProteomicsBacterial ProteinsErwinia amylovoraGene Expression Regulation, BacterialMalusPlant DiseasesPlant RootsProtein Interaction MapsProteomeReproducibility of ResultsTranscription, GeneticVirulenceBacterial ProteinsProteome

Identifiers

PMID30076380
PMCPMC6076297
OpenAlexW2885891282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.