ArticleScientific reports2018
Association between cognitive impairment and poor antihypertensive medication adherence in elderly hypertensive patients without dementia.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Guideline
- Prevalence of mild cognitive impairment in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Pooled it
- Barriers to Medication Adherence and Mild Cognitive Impairment Among African Americans with Persistently Uncontrolled Hypertension: A Cross-sectional Analysis from the Southeastern Collaboration Trial.Journal of general internal medicine · 2026Trial
- Association of Comprehensive Geriatric Assessment with Knowledge- and Technique-Related Eye Drop Adherence Problems in Glaucoma Assessed Using the Shimane University Glaucoma Eye Drop Adherence Questionnaire.Journal of clinical medicine · 2026Article
- The RESILIENT Study: A Retrospective, Descriptive, Correlational Investigation of Correlates of Oral Endocrine Therapy Adherence in Older Women With Breast Cancer.Cancer medicine · 2026Article
- Latent Class Analysis of Medication Adherence and Its Influencing Factors Among Rural Hypertensive Patients in Shanxi Province, China.Patient preference and adherence · 2026Article
- Clinical characteristics and risk factors of severe myelosuppression in rheumatoid arthritis patients with csDMARD non-adherence: a case series.Frontiers in pharmacology · 2026Review
- Promoting Medication Adherence in the Elderly: Factors and Insights From a Cross-Sectional Study.Aging medicine (Milton (N.S.W)) · 2025Article
- Navigating Health Care in Crises: Health Literacy and Treatment Adherence Among Hemodialysis Patients in Lebanon.Kidney medicine · 2025Article
- Elevating the Patient Voice: Understanding Treatment Preferences in Patients with Advanced Prostate Cancer.Advances in therapy · 2025Article
- Sex modified the association between cognitive impairment and 1-year mortality in older adults with hip fractures.Scientific reports · 2025Article
- Article
- The concordance between the Montreal cognitive assessment and the repeatable battery for the assessment of neuropsychological status as a cognitive screening tool in a south African community sample.Global mental health (Cambridge, England) · 2025Article
- Identifying the Relative Importance of Factors Influencing Medication Compliance in General Patients Using Regularized Logistic Regression and LightGBM: Web-Based Survey Analysis.JMIR formative research · 2024Article
- Article
- New insights on the link between Epstein‑Barr virus infection and cognitive decline in neurodegenerative diseases (Review).Experimental and therapeutic medicine · 2024Review
- Review
- Association between Cognitive Impairment Severity and Polypharmacy in Older Patients with Atrial Fibrillation: A Retrospective Study Using Inpatient Data from a Specialised Geriatric Hospital.Geriatrics (Basel, Switzerland) · 2024Article
- Factors associated with cognitive flexibility in people with opioid-use disorder: a pilot study.Frontiers in psychiatry · 2024Article
- Association of medication adherence quality measures for diabetes, hypertension, and hyperlipidemia with cognitive decline.Journal of family medicine and primary care · 2023Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Adherence to antihypertensive medication is a critical factor to control blood pressure and prevent complications. However, cognitive impairment can negatively affect medication adherence. In this study, we investigated the association between cognitive function and antihypertensive medication adherence among elderly hypertensive patients using the Korean National Health Insurance Service National Sample Cohort Data of the Elderly Cohort. The study included 20,071 elderly hypertensive patients and the prevalence of poor medication adherence to antihypertensive medications was 16.4%. A multivariate logistic regression analysis showed that lower cognitive function was associated with poor medication adherence (adjusted odds ratio 0.980, 95% confidence interval 0.961-0.999). Additionally, high income levels, living in metropolitan areas, and comorbidities (such as stroke, coronary heart disease, diabetes, and dyslipidemia) were positively associated with medication adherence, while patients diagnosed with cancers showed poor medication adherence. Our study demonstrated that cognitive impairment is a possible risk factor for poor antihypertensive medication adherence, even in patients without dementia. Thus, clinicians involved with geriatric care should monitor patients' cognitive function and medication adherence. And if a patient shows cognitive impairment, clinicians need to educate patients and caregivers about the importance of proper adherence, and consider proper interventions to optimize the cognitive function of elderly patients.
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