Evidence map›Paper›PMID 30076197›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Cutting Edge: Proper Orientation of CTCF Sites in Cer Is Required for Normal Jκ-Distal and Jκ-Proximal Vκ Gene Usage.

Eden Kleiman, Jeffrey Xu, Ann J Feeney

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Genome Topology Control of Antigen Receptor Gene Assembly.Journal of immunology (Baltimore, Md. : 1950) · 2020
    Review
  5. Review
  6. Two Successive Inversional Vβ Rearrangements on a SingleJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eden KleimanDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Jeffrey XuDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Ann J FeeneyDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037 feeney@scripps.edu.

Funding

Locus contraction at the Ig kappa locusR56AI119092 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI FEENEY, ANN J · 2016 to 2016
$481k
Role of chromosomal context in IgVk locus novel enhancer effects on individual Vk gene utilization, germline transcription, and long-range interactions within the Igk locusR21AI137867 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI FEENEY, ANN J · 2018 to 2018
$387k
NIAID NIH HHS R21 AI137867NIAID NIH HHS R56 AI119092
6 · The paper itself

Abstract

Igκ locus contraction and Vκ gene usage are controlled by Cer, a

Indexed as

CCCTC-Binding FactorImmunoglobulin Joining RegionImmunoglobulin kappa-ChainsAnimalsB-LymphocytesMiceMice, KnockoutResponse ElementsTranscription, GeneticCCCTC-Binding FactorCtcf protein, mouseImmunoglobulin Joining RegionImmunoglobulin kappa-Chains

Identifiers

PMID30076197
PMCPMC6125182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.