Evidence map›Paper›PMID 30076174›Full record

ArticleHaematologica2018

Non-muscle myosin II drives vesicle loss during human reticulocyte maturation.

Pedro L Moura, Bethan R Hawley, Tosti J Mankelow, Rebecca E Griffiths, Johannes G G Dobbe, Geert J Streekstra, David J Anstee, Timothy J Satchwell, Ashley M Toye

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024
    Review
  7. Neutrophils cultured ex vivo from CD34Journal of translational medicine · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Cells · 2022
    Article
  13. Article
  14. Reticulocyte Maturation.Membranes · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Altered CaCells · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Pedro L MouraSchool of Biochemistry, University of Bristol, UK.
Bethan R HawleySchool of Biochemistry, University of Bristol, UK.
Tosti J MankelowBristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.
Rebecca E GriffithsBristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.
Johannes G G DobbeDepartment of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, the Netherlands.
Geert J StreekstraDepartment of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, the Netherlands.
David J AnsteeBristol Institute for Transfusion Sciences, National Health Service Blood and Transplant (NHSBT), UK.
Timothy J SatchwellSchool of Biochemistry, University of Bristol, UK t.satchwell@bristol.ac.uk ash.m.toye@bristol.ac.uk.
Ashley M ToyeSchool of Biochemistry, University of Bristol, UK t.satchwell@bristol.ac.uk ash.m.toye@bristol.ac.uk.
University of Bristol · GBNational Health Service · GBAcademic Medical Center · NLBristol Institute for Transfusion Sciences · GBNHS Blood and Transplant · GBUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The process of maturation of reticulocytes into fully mature erythrocytes that occurs in the circulation is known to be characterized by a complex interplay between loss of cell surface area and volume, removal of remnant cell organelles and redundant proteins, and highly selective membrane and cytoskeletal remodeling. However, the mechanisms that underlie and drive these maturational processes

Indexed as

Cell DifferentiationCells, CulturedCytoplasmic VesiclesCytoskeletal ProteinsErythrocytesErythropoiesisHumansMolecular Motor ProteinsMyosin Heavy ChainsMyosin Type IIPhosphorylationProteomicsReticulocytesCytoskeletal ProteinsMolecular Motor ProteinsMYH9 protein, humanMyosin Heavy ChainsMyosin Type II

Identifiers

PMID30076174
PMCPMC6269291
OpenAlexW2885657066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.