ReviewGenome research2018
Realizing the potential of blockchain technologies in genomics.
Review in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic study on blockchain technology for genomic data management in healthcare: approaches, challenges, and research opportunities.Medical & biological engineering & computing · 2026Pooled it
- Blockchain applications in health care for COVID-19 and beyond: a systematic review.The Lancet. Digital health · 2021Pooled it
- Applications of Blockchain in the Medical Field: Narrative Review.Journal of medical Internet research · 2021Pooled it
- Aspiration to architecture: multi-omics, AI, digital twins, and blockchain for P4 medicine.Journal of translational medicine · 2026Article
- GENESIS-SHIELD: an interpretable ensemble for anomaly detection in CRISPR genomic-workflow security.Frontiers in artificial intelligence · 2026Article
- Understanding Genetic Screening: Harnessing Health Information to Prevent Disease Risks.International journal of medical sciences · 2025Review
- Genomic privacy and security in the era of artificial intelligence and quantum computing.Discover computing · 2025Review
- A framework for sharing of clinical and genetic data for precision medicine applications.Nature medicine · 2024Article
- Fortifying Health Care Intellectual Property Transactions With Blockchain.Journal of medical Internet research · 2023Review
- Role of Incentives in the Use of Blockchain-Based Platforms for Sharing Sensitive Health Data: Experimental Study.Journal of medical Internet research · 2023Article
- Amazon Biobank: a collaborative genetic database for bioeconomy development.Functional & integrative genomics · 2023Article
- Modeling the impact of data sharing on variant classification.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Telemedicine for diabetes management during COVID-19: what we have learnt, what and how to implement.Frontiers in endocrinology · 2023Review
- A scoping review of distributed ledger technology in genomics: thematic analysis and directions for future research.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Sociotechnical safeguards for genomic data privacy.Nature reviews. Genetics · 2022Review
- Storing and analyzing a genome on a blockchain.Genome biology · 2022Article
- Functional genomics data: privacy risk assessment and technological mitigation.Nature reviews. Genetics · 2022Review
- The multidimensional legal nature of personal genomic sequence data: A South African perspective.Frontiers in genetics · 2022Article
- Using game theory to thwart multistage privacy intrusions when sharing data.Science advances · 2021Article
- A Blockchain-Based Dynamic Consent Architecture to Support Clinical Genomic Data Sharing (ConsentChain): Proof-of-Concept Study.JMIR medical informatics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genomics data introduce a substantial computational burden as well as data privacy and ownership issues. Data sets generated by high-throughput sequencing platforms require immense amounts of computational resources to align to reference genomes and to call and annotate genomic variants. This problem is even more pronounced if reanalysis is needed for new versions of reference genomes, which may impose high loads to existing computational infrastructures. Additionally, after the compute-intensive analyses are completed, the results are either kept in centralized repositories with access control, or distributed among stakeholders using standard file transfer protocols. This imposes two main problems: (1) Centralized servers become gatekeepers of the data, essentially acting as an unnecessary mediator between the actual data owners and data users; and (2) servers may create single points of failure both in terms of service availability and data privacy. Therefore, there is a need for secure and decentralized platforms for data distribution with user-level data governance. A new technology, blockchain, may help ameliorate some of these problems. In broad terms, the blockchain technology enables decentralized, immutable, incorruptible public ledgers. In this Perspective, we aim to introduce current developments toward using blockchain to address several problems in omics, and to provide an outlook of possible future implications of the blockchain technology to life sciences.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.