Evidence map›Paper›PMID 30076083›Full record

ArticleAcademic radiology2019

Transfer Learning From Convolutional Neural Networks for Computer-Aided Diagnosis: A Comparison of Digital Breast Tomosynthesis and Full-Field Digital Mammography.

Kayla Mendel, Hui Li, Deepa Sheth, Maryellen Giger

Open access · greenAbstract readComparative Study
In one paragraph

Article in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Review
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  7. Article
  8. Article
  9. AMS-U-Net: automatic mass segmentation in digital breast tomosynthesis via U-Net.Journal of medical imaging (Bellingham, Wash.) · 2024
    Article
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  11. Review
  12. Article
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  16. An Automated View Classification Model for Pediatric Echocardiography Using Artificial Intelligence.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2022
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kayla MendelThe University of Chicago, 5801 S Ellis Ave, Chicago, Illinois. Electronic address: kmendel@uchicago.edu.
Hui LiThe University of Chicago, 5801 S Ellis Ave, Chicago, Illinois.
Deepa ShethThe University of Chicago, 5801 S Ellis Ave, Chicago, Illinois.
Maryellen GigerThe University of Chicago, 5801 S Ellis Ave, Chicago, Illinois.
University of Chicago · US

Funding

Developing an Oncology Workforce for the 21st Century - Renewal 01K12CA139160 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F., SMITH, SONALI · 2010 to 2024
$10.6M
RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
UChicago Interdisciplinary Cancer Health Disparities SPOREP20CA233307 · NCI · UNIVERSITY OF CHICAGO · PI HUO, DEZHENG, NANDA, RITA · 2018 to 2020
$3.4M
Quantitative Image Analysis for Assessing Response to Breast Cancer TherapyU01CA195564 · NCI · UNIVERSITY OF CHICAGO · PI GIGER, MARYELLEN L. · 2015 to 2019
$2.5M
NCI NIH HHS K12 CA139160NCI NIH HHS P20 CA233307NCI NIH HHS U01 CA195564NIBIB NIH HHS T32 EB002103
6 · The paper itself

Abstract

RATIONALE AND

objectivesWith the growing adoption of digital breast tomosynthesis (DBT) in breast cancer screening, we compare the performance of deep learning computer-aided diagnosis on DBT images to that of conventional full-field digital mammography (FFDM). MATERIALS AND

methodsIn this study, we retrospectively collected FFDM and DBT images of 78 biopsy-proven lesions from 76 patients. A region of interest was selected for each lesion on FFDM, synthesized 2D, and DBT key slice images. Features were extracted from each lesion using a pretrained convolutional neural network (CNN) and served as input to a support vector machine classifier trained in the task of predicting likelihood of malignancy.

resultsFrom receiver operating characteristic (ROC) analysis of all 78 lesions, the synthesized 2D image performed best in both the cradiocaudal view (area under the ROC curve [AUC] = 0.81, SE = 0.05) and mediolateral oblique view (AUC = 0.88, SE = 0.04) in the task of lesion characterization. When cradiocaudal and mediolateral oblique data of each lesion were merged through soft voting, DBT key slice image performed best (AUC = 0.89, SE = 0.04). When only masses and architectural distortions (ARDs) were considered, DBT performed significantly better than FFDM (p = 0.024).

conclusionDBT performed significantly better than FFDM in the merged view classification of mass and ARD lesions. The increased performance suggests that the information extracted by the CNN from DBT images may be more relevant to lesion malignancy status than the information extracted from FFDM images. Therefore, this study provides supporting evidence for the efficacy of computer-aided diagnosis on DBT in the evaluation of mass and ARD lesions.

Indexed as

Neural Networks, ComputerAdultAgedBreastBreast NeoplasmsFemaleHumansMachine LearningMammographyMiddle AgedRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesROC CurveComputer-aided diagnosisConvolutional neural networksDeep learningDigital breast tomosynthesisMammography

Identifiers

PMID30076083
PMCPMC6355376
OpenAlexW2885841583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.