ArticleBMC genomics2018
Comparative transcriptomics reveals suppressed expression of genes related to auxin and the cell cycle contributes to the resistance of cucumber against Meloidogyne incognita.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 41 citations in OpenAlex.
- Review
- Comprehensive analysis of the GeBP gene family in cucumber highlights functional divergence in fruit development and stress tolerance.BMC plant biology · 2026Article
- Evolutionary and Functional Characterization of an Auxin Methyltransferase (Ecology and evolution · 2026Article
- Molecular Mechanisms ofInternational journal of molecular sciences · 2026Article
- Integrated multi-omics analysis reveals the response mechanisms ofFrontiers in plant science · 2026Article
- Identification of MYC genes in four Cucurbitaceae species and their roles in the response to temperature stress.BMC genomics · 2024Article
- Article
- Integrated Omic Approaches Reveal Molecular Mechanisms of Tolerance during Soybean andPlants (Basel, Switzerland) · 2022Article
- Local auxin synthesis mediated by YUCCA4 induced during root-knot nematode infection positively regulates gall growth and nematode development.Frontiers in plant science · 2022Article
- Genome-Wide Identification, Phylogenetic and Expression Pattern Analysis of GATA Family Genes in Cucumber (Plants (Basel, Switzerland) · 2021Article
- Efficacy of a Chitin-Based Water-Soluble Derivative in InducingInternational journal of molecular sciences · 2021Article
- Whole-Genome Sequence of Synthesized Allopolyploids inAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Transcriptomic and Histological Analysis of the Response of Susceptible and Resistant Cucumber toFrontiers in plant science · 2021Article
- Transcriptomic profiling of Solanum peruvianum LA3858 revealed a Mi-3-mediated hypersensitive response to Meloidogyne incognita.BMC genomics · 2020Article
- Identification and Expression Analysis of theFrontiers in genetics · 2020Article
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9 authors at 1 institution in 1 country.
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Abstract
backgroundMeloidogyne incognita is a devastating nematode that causes significant losses in cucumber production worldwide. Although numerous studies have emphasized on the susceptible response of plants after nematode infection, the exact regulation mechanism of M. incognita-resistance in cucumber remains elusive. Verification of an introgression line, 'IL10-1', with M. incognita-resistance provides the opportunity to unravel the resistance mechanism of cucumber against M. incognita.
resultsIn the present study, analyses of physiological responses and transcriptional events between IL10-1 (resistant line) and CC3 (susceptible line) were conducted after M. incognita infection. Physiological observations showed abnormal development of giant cells and M. incognita in IL10-1, which were the primary differences compared with CC3. Furthermore, Gene ontology (GO) analysis revealed that genes encoding cell wall proteins were up-regulated in IL10-1 and that the highly expressed lipid transfer protein gene (Csa6G410090) might be the principal regulator of this up-regulation. Simultaneously, analyses of gene expression profiles revealed more auxin-related genes were suppressed in IL10-1 than in those of CC3, which corresponded with the lower level of indole acetic acid (IAA) in the roots of IL10-1 than in those of CC3. Additionally, poor nucleus development as a clear indication of abnormal giant cells in IL10-1 was related to inhibition of the cell cycle. Of those genes related to the cell cycle, the F-box domain Skp2-like genes were down-regulated in IL10-1, whereas more of these genes were up-regulated in CC3.
conclusionsAll of these findings indicate that suppressed expression of genes related to auxin and the cell cycle and highly expressed cell wall proteins play important roles in the abnormal development of giant cells, which hinders the development of M. incognita, thereby causing resistance to M. incognita in IL10-1. Knowledge from this research will provide a useful foundation for developing effective strategies in M. incognita-resistance breeding.
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