Evidence map›Paper›PMID 30075717›Full record

ArticleRespiratory research2018

The diagnostic performance of patient symptoms in screening for COPD.

Kate M Johnson, Wan C Tan, Jean Bourbeau, Don D Sin, Mohsen Sadatsafavi, Canadian Cohort of Obstructive Lung Disease (CanCOLD) study and the Canadian Respiratory Research Network

Open access · goldAbstract readLetter
In one paragraph

Article in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kate M JohnsonRespiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.ORCID 0000-0001-7406-2448
Wan C TanCentre for Heart Lung Innovation (the James Hogg Research Centre), St. Paul's Hospital, Vancouver, Canada.
Jean BourbeauRespiratory Epidemiology and Clinical Research Unit, McGill University, Montreal, Canada.
Don D SinCentre for Heart Lung Innovation (the James Hogg Research Centre), St. Paul's Hospital, Vancouver, Canada.
Mohsen SadatsafaviRespiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada. msafavi@mail.ubc.ca.
Canadian Cohort of Obstructive Lung Disease (CanCOLD) study and the Canadian Respiratory Research Network
University of British Columbia · CAMcGill University · CASt. Paul's Hospital · CAVancouver Coastal Health · CA

Funding

CIHR 142238CIHR 93326
6 · The paper itself

Abstract

It is recommended that screening for COPD be restricted to symptomatic individuals, but supporting evidence is lacking. We determined the performance of wheeze, cough, phlegm, and dyspnea in discriminating COPD versus non-COPD in a population-based sample of 1332 adults. Area Under the Receiver Operating Curves (AUC) indicated that symptoms had modest performance whether assessed individually (AUCs 0.55-0.62), or in combination (AUC for number of symptoms as the predictor 0.64). AUC improved with the inclusion of multiple other factors (AUC 0.71). Restricting screening to symptomatic individuals is unlikely to substantially improve the yield of general population screening for undiagnosed COPD.

Indexed as

Surveys and QuestionnairesAgedCanadaCohort StudiesCoughDyspneaFemaleHumansMaleMass ScreeningMiddle AgedPulmonary Disease, Chronic ObstructiveSmokingSpirometryChronic obstructive pulmonary diseasePopulationRespiratory symptomsScreening test

Identifiers

PMID30075717
PMCPMC6090694
OpenAlexW2886624354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.