Evidence map›Paper›PMID 30075592›Full record

ArticleMedicine2018

The increase in total knee replacement surgery in Taiwan: A 15-year retrospective study.

Fu-Huang Lin, Hsiang-Cheng Chen, Chin Lin, Yu-Lung Chiu, Herng-Sheng Lee, Hung Chang, Guo-Shu Huang, Hsueh-Lu Chang, Shih-Jen Yeh, Wen Su and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06562101 (Effects of Intra-articular Stromal Vascular Fraction Injection on Clinical Symptoms and Cartilage Health in Osteoarthritic Knees), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06562101 nacompletednot on this mapstarted 2020, after this paper: background citation

Effects of Intra-articular Stromal Vascular Fraction Injection on Clinical Symptoms and Cartilage Health in Osteoarthritic Knees: A Single-Center Pilot Study

TypeinterventionalSponsorShu-Hao Chang, MDRan2020 to 2022Enrolled10ConditionsOsteoarthritis, KneeArmsIntra-articular Stromal Vascular Fraction Injection
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  8. Mesenchymal Stromal Cells for Aging Cartilage Regeneration: A Review.International journal of molecular sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fu-Huang LinSchool of Public Health Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung Department of Physiology and Biophysics Division of Thoracic Surgery Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei Department of Research and Development, Da-Yeh University, Changhua Department of Nursing Department of Orthopedics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Hsiang-Cheng Chen
Chin Lin
Yu-Lung Chiu
Herng-Sheng Lee
Hung Chang
Guo-Shu Huang
Hsueh-Lu Chang
Shih-Jen Yeh
Wen Su
Chih-Chien Wang
Sui-Lung Su

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Total knee replacement (TKR) is considered as one of the most success among clinical interventions for patients with who suffering from knee osteoarthritis (OA). We sought to estimate the incidence of TKR using demographics, incidence rates, lengths of hospital stay, and costs from 1996 to 2010 by analyzing Taiwan's National Health Insurance Research Database. A total of 154,553 patients obtained primary TKR surgery between 1996 and 2010. The diagnosis code for knee OA and the procedure code for TKR were selected from the records. To compare the rate of TKR between covariables, we calculated the TKR risk ratios and 95% confidence interval (CI) of these variables (gender, age, age group, and primary diagnoses). A 2-tailed P-value of .05 was considered statistically significant. The statistical package SPSS version 20.0 (SPSS, Chicago, IL) was used to conduct all the statistical analyzes. We analyzed 154,553 TKRs performed by surgeons in Taiwan from 1996 to 2010. The overall crude incidence increased from 26.4 to 74.55 TKR per 100,000 inhabitants from 1996 to 2010. TKR incidence for the 70 to 79 years age group increased from 227 to 505 per 100,000 people from 1996 to 2010. The age-standardized rate ratios for TKR of women to men ranged from 2.5 to 3.0. The mean average length of stay in hospital was 15 days in 1996 and decreased to 8 days in 2010. During the study period, the adjusted mean cost per patient decreased from US$7485 to US$4827. Health expenditures for TKR were 5% of total National Health Insurance expenditure every year. Over the 15-year period, Taiwan's TKR incidence tripled, which is consistent with population ageing. Arthritis will be a major public health issue in the ageing population in the future.

Indexed as

AgedAged, 80 and overAge DistributionArthroplasty, Replacement, KneeCosts and Cost AnalysisFemaleHumansIncidenceLength of StayMaleMiddle AgedNational Health ProgramsOsteoarthritis, KneeRetrospective StudiesSex DistributionSocioeconomic Factors

Identifiers

PMID30075592
PMCPMC6081077

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.