Observational studyMedicine2018
Prevalence triggers and clinical severity associated with anaphylaxis at a tertiary care facility in Saudi Arabia: A cross-sectional study.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Global patterns in anaphylaxis due to specific foods: A systematic review.The Journal of allergy and clinical immunology · 2021Pooled it
- Teachers' Knowledge and Attitude toward Anaphylaxis in Saudi Arabia.Annals of African medicine · 2025Article
- Assessing Preparedness and Preventive Measures for Managing Food Allergy and Anaphylaxis in Primary Schools of Rabigh, Saudi Arabia.International journal of environmental research and public health · 2025Article
- Public Knowledge and Management Practices of Anaphylaxis in Al-Ahsa, Saudi Arabia: A Cross-Sectional Study.Cureus · 2025Article
- Article
- School Teachers' Knowledge and Attitudes Related to Anaphylactic Reactions: A Cross-Sectional Study.Cureus · 2024Article
- Drug-induced hypersensitivity reactions in a Lebanese outpatient population: A decade-long retrospective analysis (2012-2021).The journal of allergy and clinical immunology. Global · 2024Article
- Drug-Induced Anaphylaxis: National Database Analysis.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Awareness of anaphylaxis among public in Al-Ahsa City of Saudi Arabia: A cross-sectional study.PloS one · 2024Article
- Level of Awareness of Certified Non-critical Care Physicians in Diagnosing, Managing, and Disposing Anaphylactic Cases.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024Article
- Latin American anaphylaxis registry.The World Allergy Organization journal · 2023Article
- Prevalence of Food Allergy and Common Food Allergen Among Saudi Adults in Makkah Region, Saudi Arabia.Journal of asthma and allergy · 2022Article
- Anaphylaxis in Omani Patients: A Study from a Tertiary Care Center.Oman medical journal · 2022Article
- Responses of consumers with food allergy to the new allergen-labelling legislation in Saudi Arabia: a preliminary survey.Public health nutrition · 2021Observational
- Saudi teachers' confidence and attitude about their role in anaphylaxis management.Journal of family medicine and primary care · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anaphylaxis is a systemic and hypersensitive allergic reaction caused by various triggers such as environmental, food, drug, and insects. The aim of this study was to identify the prevalence, triggers, and clinical severity of anaphylaxis in 2 emergency departments (EDs) in Saudi Arabia.A cross-sectional study based on a screening of medical records was conducted between January 2015 and August 2017, to identify confirmed cases of anaphylaxis. Patient characteristics were age, sex, previously known allergies, and the triggering allergens. The clinical severity was measured on the basis of the anaphylaxis international assessment tool (mild, moderate, severe). Factors associated with triggers and severities were identified.The period prevalence of anaphylaxis among ED admissions was 0.00026%. Pediatric cases (age 1-16 years) were 98 (60.9%), while adults (age 17-40 years) were 63 (39.1%). Triggers of anaphylaxis were food 63 (39.1%), insects 62 (38.5%), drugs 28 (17.4%), and environmental 8 (5.0%). Mild symptoms were observed in 41 (25%) of the sample, while moderate and severe symptoms were observed in 116 (72%) and 4 (3%) of the cases, respectively. Adults were 1.25 times more likely to endure drug allergy rather than food allergy, than pediatrics with adj.P = .015. ED admissions in summer season were 1.29 less likely to be due to drug allergy rather than insect allergy, compared with admissions in winter season, adj.P = .01. Cases with known allergy were 1.72 times less likely to endure drug allergy rather than food allergy, compared with those with unknown allergy, adj.P = .001. Adults were 4.79 more likely to endure severe symptoms than pediatrics with adj.P = .001.Although the prevalence of anaphylaxis was higher in pediatrics, yet the disease was more severe in adults. Special consideration should be paid to anaphylaxis triggered by insect bites in summer, and food allergy among cases with unknown allergy upon ED admission.
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