ArticleDevelopmental cognitive neuroscience2018
Human amygdala functional network development: A cross-sectional study from 3 months to 5 years of age.
Article in Developmental cognitive neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 50 citations in OpenAlex.
- Preliminary examination of the effects of an early parenting intervention on amygdala-orbitofrontal cortex resting-state functional connectivity among high-risk children: A randomized clinical trial.Development and psychopathology · 2025Trial
- Thalamic reticular nucleus in the pathophysiology of schizophrenia.Neural regeneration research · 2026Article
- Neonatal amygdala and fear processing across early childhood.European child & adolescent psychiatry · 2026Article
- The promise of infant MRI in psychiatry: toward a framework for neural network measures in early emotional and behavioral risk identification and new intervention targets.Molecular psychiatry · 2026Review
- Directional flow of brain connections and neurodevelopmental outcomes in healthy full-term newborns.Neuroscience letters · 2025Article
- Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry.Cell reports · 2025Article
- Amygdala-hippocampus connectivity and childhood depressive symptoms: subnuclei insights and self-concept roles.Translational psychiatry · 2025Article
- Narrative Review: A Neurobiological Perspective on Resilience in Youth.JAACAP open · 2025Review
- Developmental changes in brain-wide fear memory networks.Neurobiology of learning and memory · 2025Article
- The Journey of the Default Mode Network: Development, Function, and Impact on Mental Health.Biology · 2025Review
- Maternal prenatal social disadvantage and neonatal functional connectivity: Associations with psychopathology symptoms at age 12 months.Developmental psychology · 2024Article
- Associations between infant amygdala functional connectivity and social engagement following a stressor: A preliminary investigation.Developmental science · 2024Article
- Failure to breathe persists without air hunger or alarm following amygdala seizures.JCI insight · 2023Article
- Age-related differences in resting-state functional connectivity from childhood to adolescence.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Early life factors and hippocampal functional connectivity in children with overweight/obesity.Pediatric obesity · 2023Article
- Extinction Learning Across Development: Neurodevelopmental Changes and Implications for Pediatric Anxiety Disorders.Current topics in behavioral neurosciences · 2023Article
- COVID-19 and the Infant Brain: Critical Links Among Prenatal Maternal Distress, Social Support, and Neurodevelopment.Biological psychiatry · 2022Article
- Amygdala-prefrontal connectivity in children with maladaptive aggression is modulated by social impairment.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Heterogeneity in PFC-amygdala connectivity in middle childhood, and concurrent interrelations with inhibitory control and anxiety symptoms.Neuropsychologia · 2022Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
Although the amygdala's role in shaping social behavior is especially important during early post-natal development, very little is known of amygdala functional development before childhood. To address this gap, this study uses resting-state fMRI to examine early amygdalar functional network development in a cross-sectional sample of 80 children from 3-months to 5-years of age. Whole brain functional connectivity with the amygdala, and its laterobasal and superficial sub-regions, were largely similar to those seen in older children and adults. Functional distinctions between sub-region networks were already established. These patterns suggest many amygdala functional circuits are intact from infancy, especially those that are part of motor, visual, auditory and subcortical networks. Developmental changes in connectivity were observed between the laterobasal nucleus and bilateral ventral temporal and motor cortex as well as between the superficial nuclei and medial thalamus, occipital cortex and a different region of motor cortex. These results show amygdala-subcortical and sensory-cortex connectivity begins refinement prior to childhood, though connectivity changes with associative and frontal cortical areas, seen after early childhood, were not evident in this age range. These findings represent early steps in understanding amygdala network dynamics across infancy through early childhood, an important period of emotional and cognitive development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.