Evidence map›Paper›PMID 30075054›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2018

Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity.

Gina N Woods, Susan K Ewing, Sigurdur Sigurdsson, Deborah M Kado, Joachim H Ix, Trisha F Hue, Gudny Eiriksdottir, Kaipin Xu, Vilmundur Gudnason, Thomas F Lang and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Gina N WoodsDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Susan K EwingDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Sigurdur SigurdssonIcelandic Heart Association, Kopavogur, Iceland.
Deborah M KadoDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Joachim H IxDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Trisha F HueDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Gudny EiriksdottirIcelandic Heart Association, Kopavogur, Iceland.
Kaipin XuDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.
Vilmundur GudnasonIcelandic Heart Association, Kopavogur, Iceland.
Thomas F LangDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Tamara B HarrisIntramural Research Program, National Institute on Aging, Bethesda, MD, USA.
Clifford J RosenMaine Medical Center Research Institute, Scarborough, ME, USA.
Xiaojuan LiDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.
Ann V SchwartzDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
University of California, San Francisco · USIcelandic Heart Association · ISCleveland Clinic · USVA San Diego Healthcare System · USMaine Medical Center · USNational Institute on Aging · USUniversity of California System · US

Funding

Longitudinal changes in marrow fat, other fat depots and boneR01AR065645 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LI, XIAOJUAN, SCHWARTZ, ANN V · 2014 to 2017
$2.2M
Bone Marrow Adiposity, Bone and Body CompositionR01AR057819 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LI, XIAOJUAN, SCHWARTZ, ANN V · 2010 to 2012
$1.7M
AGES STUDY-THE REYKJAVIK STUDY OF HEALTHY AGING FOR THE NEW MILLENNIUM-26012100N01AG012100 · NIA · ICELANDIC HEART ASSOCIATION · 2002 to 2004
–
Intramural NIH HHS Z99 AG999999NIAMS NIH HHS R01 AR057819NIAMS NIH HHS R01 AR065645NIA NIH HHS N01 AG012100
6 · The paper itself

Abstract

Bone marrow adiposity is associated with aging, osteoporosis, and reduced hematopoiesis, as well as anorexia nervosa, but little is known about the underlying mechanisms that affect marrow adiposity. Chronic kidney disease (CKD) may influence bone marrow adipose tissue (BMAT), possibly through loss of lean mass or higher circulating levels of sclerostin. To test these hypotheses, we investigated the cross-sectional association between estimated glomerular filtration rate (eGFR) as a measure of kidney function and

Indexed as

Adipose TissueAdiposityAged, 80 and overBone MarrowFemaleGlomerular Filtration RateHumansMaleRenal Insufficiency, Chronic

Identifiers

PMID30075054
PMCPMC6702945
OpenAlexW2885659225

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.