Evidence map›Paper›PMID 30074996›Full record

Trial reportPloS one2018

Individually-tailored multifactorial intervention to reduce falls in the Malaysian Falls Assessment and Intervention Trial (MyFAIT): A randomized controlled trial.

Pey June Tan, Ee Ming Khoo, Karuthan Chinna, Nor I'zzati Saedon, Mohd Idzwan Zakaria, Ahmad Zulkarnain Ahmad Zahedi, Norlina Ramli, Nurliza Khalidin, Mazlina Mazlan, Kok Han Chee and 15 more

Abstract readPragmatic Clinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Multi-Factorial and Multi-Component Fall Prevention Interventions Initiated From the Emergency Department: A Systemic Review and Meta-Analysis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
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  9. Pragmatic clinical trial design in emergency medicine: Study considerations and design types.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2022
    Article
  10. Moving the needle on fall prevention: A Geriatric Emergency Care Applied Research (GEAR) Network scoping review and consensus statement.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021
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  15. The Efficacy of Fall Hazards Identification on Fall Outcomes: A Systematic Review With Meta-analysis.Archives of rehabilitation research and clinical translation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Pey June TanAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Ee Ming KhooDepartment of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Karuthan ChinnaDepartment of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nor I'zzati SaedonAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Mohd Idzwan ZakariaDepartment of Trauma and Emergency Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Ahmad Zulkarnain Ahmad ZahediDepartment of Trauma and Emergency Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Norlina RamliDepartment of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nurliza KhalidinDepartment of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Mazlina MazlanDepartment of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Limpur, Malaysia.
Kok Han CheeDivision of Cardiology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Imran Zainal AbidinDivision of Cardiology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nemala NalathambyAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Sumaiyah MatAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Mohamad Hasif JaafarAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Hui Min KhorAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Norfazilah Mohamad KhannasDepartment of Rehabilitation Medicine, Kuala Lumpur, University of Malaya Medical Centre, Kuala Limpur, Malaysia.
Lokman Abdul MajidDepartment of Rehabilitation Medicine, Kuala Lumpur, University of Malaya Medical Centre, Kuala Limpur, Malaysia.
Kit Mun TanAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Ai-Vyrn ChinAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Shahrul Bahyah KamaruzzamanAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Philip PoiAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.
Karen MorganDepartment Psychology and Behavioural Science, Perdana University-RCSI School of Medicine, Serdang, Selangor, Malaysia.
Keith D HillSchool of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, Australia.
Lynette MacKenzieDepartment of Occupational Therapy, Faculty of Health Sciences, University of Sydney, Sydney, Australia.
Maw Pin TanAgeing and Age-Associated Disorders Research Group, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-3400-8540

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the effectiveness of an individually-tailored multifactorial intervention in reducing falls among at risk older adult fallers in a multi-ethnic, middle-income nation in South-East Asia.

designPragmatic, randomized-controlled trial.

settingEmergency room, medical outpatient and primary care clinic in a teaching hospital in Kuala Lumpur, Malaysia.

participantsIndividuals aged 65 years and above with two or more falls or one injurious fall in the past 12 months.

interventionIndividually-tailored interventions, included a modified Otago exercise programme, HOMEFAST home hazards modification, visual intervention, cardiovascular intervention, medication review and falls education, was compared against a control group involving conventional treatment. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was any fall recurrence at 12-month follow-up. Secondary outcomes were rate of fall and time to first fall.

resultsTwo hundred and sixty-eight participants (mean age 75.3 ±7.2 SD years, 67% women) were randomized to multifactorial intervention (n = 134) or convention treatment (n = 134). All participants in the intervention group received medication review and falls education, 92 (68%) were prescribed Otago exercises, 86 (64%) visual intervention, 64 (47%) home hazards modification and 51 (38%) cardiovascular intervention. Fall recurrence did not differ between intervention and control groups at 12-months [Risk Ratio, RR = 1.037 (95% CI 0.613-1.753)]. Rate of fall [RR = 1.155 (95% CI 0.846-1.576], time to first fall [Hazard Ratio, HR = 0.948 (95% CI 0.782-1.522)] and mortality rate [RR = 0.896 (95% CI 0.335-2.400)] did not differ between groups.

conclusionIndividually-tailored multifactorial intervention was ineffective as a strategy to reduce falls. Future research efforts are now required to develop culturally-appropriate and affordable methods of addressing this increasingly prominent public health issue in middle-income nations.

trial registrationISRCTN Registry no. ISRCTN11674947.

Indexed as

Accidental FallsAccidents, HomeAgedAged, 80 and overCardiovascular DiseasesEmergency Service, HospitalEnvironment DesignExercise TherapyFemaleHumansMalaysiaMalePatient AdmissionPrecision MedicinePrimary PreventionVision Disorders

Identifiers

PMID30074996
PMCPMC6075745

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.