Evidence map›Paper›PMID 30074430›Full record

ArticlePrion2018

Poly-L-histidine inhibits prion propagation in a prion-infected cell line.

Ryo Honda, Kei-Ichi Yamaguchi, Abdelazim Elsayed Elhelaly, Mitsuhiko Fuji, Kazuo Kuwata

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Prion, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Delayed progression of prion disease in mice by polyarginine-facilitated prevention of PrPNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  2. The Effect ofInternational journal of molecular sciences · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ryo Hondaa United Graduate School of Drug Discovery and Medical Information Sciences , Gifu University , Gifu , Japan.ORCID 0000-0003-3698-5975
Kei-Ichi Yamaguchib Institute for Protein Research , Osaka University , Osaka , Japan.
Abdelazim Elsayed Elhelalya United Graduate School of Drug Discovery and Medical Information Sciences , Gifu University , Gifu , Japan.
Mitsuhiko Fujia United Graduate School of Drug Discovery and Medical Information Sciences , Gifu University , Gifu , Japan.
Kazuo Kuwataa United Graduate School of Drug Discovery and Medical Information Sciences , Gifu University , Gifu , Japan.
Gifu University · JPProtein Research Foundation · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transmissible spongiform encephalopathies (TSEs) are a group of lethal neurodegenerative diseases involving the structural conversion of cellular prion protein (PrP

Indexed as

AnimalsCell Line, TumorHistidineHumansMagnetic Resonance SpectroscopyMaleMicePrion DiseasesPrion ProteinsPrPC ProteinsPrPSc ProteinsHistidinepolyhistidinePrion ProteinsPrPC ProteinsPrPSc Proteins

Identifiers

PMID30074430
PMCPMC6277182
OpenAlexW2885388333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.