Evidence map›Paper›PMID 30074101›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2020

Outcomes following percutaneous tibial nerve stimulation (PTNS) treatment for neurogenic and idiopathic overactive bladder.

Katarina Ivana Tudor, Jai H Seth, Martina D Liechti, Juliana Ochulor, Gwen Gonzales, Collette Haslam, Zoe Fox, Mahreen Pakzad, Jalesh N Panicker

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Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Katarina Ivana TudorDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK. katarina.ivana.tudor@kbc-zagreb.hr.ORCID 0000-0002-5293-1646
Jai H SethDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Martina D LiechtiDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Juliana OchulorDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Gwen GonzalesDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Collette HaslamDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Zoe FoxBiostatistics Group, University College London Hospitals and University College London Research Support Centre, University College London, London, UK.
Mahreen PakzadDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
Jalesh N PanickerDepartment of Uro-Neurology, The National Hospital for Neurology and Neurosurgery, UCL Institute of Neurology, Queen Square, London, UK.
National Hospital for Neurology and Neurosurgery · GBRoyal London Hospital · GBUniversity Hospital Centre Zagreb · HRUniversity of Zurich · CH

Funding

Department of Health
6 · The paper itself

Abstract

purposePercutaneous tibial nerve stimulation is a minimally invasive neuromodulation technique for treating overactive bladder symptoms. The aim of this study was to assess safety, efficacy and impact on quality of life of percutaneous tibial nerve stimulation in neurological patients reporting overactive bladder symptoms.

methodsIn this retrospective evaluation over 18 months at a tertiary healthcare centre, patients finding first-line treatments for overactive bladder ineffective or intolerable underwent a standard 12-week course of percutaneous tibial nerve stimulation (Urgent PC, Uroplasty). Symptoms were evaluated using standardised International Consultation on Incontinence Questionnaires and bladder diaries.

resultsOf 74 patients (52 women, 22 men, mean age 56 years), 49 (66.2%) patients had neurological disorder [19 (25.7%) multiple sclerosis and 30 (40.5%) other neurological conditions] and 25 (33.8%) idiopathic overactive bladder. Overall for the entire cohort significant improvements were recorded after 12 weeks in the following domains: 24-h frequency on bladder diary - 1.67 (- 3.0, 0.33) (p = 0.002), number of incontinent episodes on bladder diary - 0.0 (- 1, 0) (p = 0.01), incontinence severity on bladder diary 0 (- 0.33, 0) (p = 0.007), OAB symptoms - 3 (- 11.5, 5) (p = 0.01), and quality of life - 16 (- 57, 6.5) (p = 0.004). There were no significant differences in outcomes between patients with idiopathic and neurogenic overactive bladder.

conclusionsPercutaneous tibial nerve stimulation appears to be a possible promising alternative for patients with neurological disorder reporting overactive bladder symptoms who find first-line treatments either ineffective or intolerable. However, a properly designed study is required to address safety and efficacy.

Indexed as

AdultAgedCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesTibial NerveTranscutaneous Electric Nerve StimulationTreatment OutcomeUrinary Bladder, OveractiveUrinary IncontinenceLower urinary tract symptomsMultiple sclerosisOveractive bladderPercutaneous electric nerve stimulationQuality of life

Identifiers

PMID30074101
OpenAlexW2887290231

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.