Evidence map›Paper›PMID 30073755›Full record

ReviewJournal of cellular and molecular medicine2018

The emerging role of miR-19 in glioma.

Weihan Wang, Anling Zhang, Yubing Hao, Guangxiu Wang, Zhifan Jia

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

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  10. Up-regulation of MARVEL domain-containing protein 1 (MARVELD1) accelerated the malignant phenotype of glioma cancer cells via mediating JAK/STAT signaling pathway.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
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  20. The emerging role of miR-19 in glioma.Journal of cellular and molecular medicine · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Weihan WangDepartment of Neurosurgery, Tianjin Medical University, General Hospital, Tianjin Neurological Institute, Laboratory of Neuro-Oncology, Key Laboratory of Post-Trauma Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin, China.
Anling ZhangDepartment of Neurosurgery, Tianjin Medical University, General Hospital, Tianjin Neurological Institute, Laboratory of Neuro-Oncology, Key Laboratory of Post-Trauma Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin, China.
Yubing HaoDepartment of Neurosurgery, Tianjin Medical University, General Hospital, Tianjin Neurological Institute, Laboratory of Neuro-Oncology, Key Laboratory of Post-Trauma Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin, China.
Guangxiu WangDepartment of Neurosurgery, Tianjin Medical University, General Hospital, Tianjin Neurological Institute, Laboratory of Neuro-Oncology, Key Laboratory of Post-Trauma Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin, China.
Zhifan JiaDepartment of Neurosurgery, Tianjin Medical University, General Hospital, Tianjin Neurological Institute, Laboratory of Neuro-Oncology, Key Laboratory of Post-Trauma Neuro-Repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin, China.ORCID 0000-0003-2104-0741
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma has been regarded as the most common, highly proliferative and invasive brain tumour. Advances in research of miRNAs in glioma are toward further understanding of the pathogenesis of glioma. MiR-19, a member of miR-17~92 cluster, was reported to play an oncogenic role in tumourigenesis. Here we review the identified data about the effect of miR-19 on proliferation, apoptosis, migration and invasion of glioma cells, the target genes regulated by miR-19, and correlation of miR-19 with the sensitivity of glioma cells to chemotherapy and radiotherapy. It is concluded that miR-19 plays an important role in the pathogenesis of glioma and can be a potential target for gene therapy of glioma.

Indexed as

Gene Expression Regulation, NeoplasticAntineoplastic AgentsApoptosisBrain NeoplasmsCarcinogenesisCell MovementCell ProliferationGamma RaysGenetic TherapyGliomaHumansMicroRNAsNeoplasm InvasivenessNeoplasm ProteinsRadiation ToleranceSignal TransductionAntineoplastic AgentsMicroRNAsMIRN19A microRNA, humanNeoplasm ProteinschemotherapygliomamiR-19radiotherapytarget gene

Identifiers

PMID30073755
PMCPMC6156349
OpenAlexW2886286785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.