Evidence map›Paper›PMID 30073635›Full record

ArticleAIDS and behavior2018

Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa.

Hyunsuk Yoo, Juyeon Lee, Jae-Joon Yim, Till Bärnighausen, Frank Tanser, Sue K Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyunsuk YooDepartment of Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Juyeon LeeDepartment of Preventive Medicine, Seoul National University College of Medicine, 103 Daehakno, Jongro-Gu, Seoul, 110-799, South Korea.
Jae-Joon YimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
Till BärnighausenDepartment of Global Health and Population, Harvard School of Public Health, Boston, MA, USA.
Frank TanserAfrica Health Research Institute, KwaZulu-Natal, South Africa. ftanser@gmail.com.
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, 103 Daehakno, Jongro-Gu, Seoul, 110-799, South Korea. suepark@snu.ac.kr.ORCID http://orcid.org/0000-0001-5002-9707

Funding

Training Tanzanian Researchers for HIV/AIDS Implementation ScienceD43TW009775 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, Christopher Sudfeld · 2015 to 2026
$3.0M
Causal Pathways to population health impact of HIV antiretroviral treatmentR01HD084233 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2015 to 2021
$2.3M
Can HIV Hot-Spots be eradicated? An intervention to decrease HIV transmission to young women in rural KwaZulu-Natal South AfricaR01AI124389 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2016 to 2020
$2.1M
FIC NIH HHS D43 TW009775FIC of NIH D43-TW009775NIAID NIH HHS R01 AI124389NIAID of NIH R01- AI124389NICHD NIH HHS R01 HD084233NICHD of NIH R01-HD084233South African MRC Flagship MRC-RFA-UFSP-01-2013/UKZN HIVEPIUK Academy of Medical Sciences Newton Advanced Fellowship NA150161Wellcome Trust
6 · The paper itself

Abstract

We investigated whether mortality risk increases with the number of full-term pregnancies in HIV-infected women. Our study is based on data from the ACDIS cohort, collected in rural KwaZulu-Natal, South Africa. Mortality risk for different number of pregnancies in HIV-infected women was analyzed using Cox proportional hazards model. The risk of TB or AIDS mortality in HIV-uninfected women did not change with the number of full-term pregnancies, while the corresponding risk increased markedly in HIV-infected women. The risk of TB or AIDS mortality increased 1.48-fold (95% CI 1.25-1.75), 1.76-fold (95% CI 1.45-2.13), and 1.59-fold (95% CI 1.31-1.94) for one, two, and three or more full-term pregnancies compared to none, respectively. Finally, women who are young (age < 26) have greater risk of TB or AIDS mortality compared to women who are old (age ≥ 26), and women residing in rural areas have greater risk compared to women who reside in non-rural areas.

Indexed as

Rural PopulationAdolescentAdultAIDS-Related Opportunistic InfectionsCohort StudiesFemaleHIV InfectionsHumansMiddle AgedPregnancyPregnancy Complications, InfectiousProspective StudiesRisk FactorsRural HealthSouth AfricaTuberculosisAIDSHIVMortalityPregnancyTuberculosis

Identifiers

PMID30073635
PMCPMC6208905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.