Evidence map›Paper›PMID 30073624›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018

Low iris and anterior chamber volume is associated with deepening after laser peripheral iridotomy in primary angle closure suspects.

Hamed Esfandiari, Mohammad Pakravan, Nassim Amouhashemi, Mehdi Yaseri, Pooya Torkian, Khosrow Jadidi, Nils A Loewen

Open access · greenAbstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Hamed EsfandiariDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St., Pittsburgh, PA, 15213, USA.
Mohammad PakravanOphthalmic Epidemiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nassim AmouhashemiOphthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehdi YaseriDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Pooya TorkianOphthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Khosrow JadidiDepartment of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Nils A LoewenDepartment of Ophthalmology, School of Medicine, University of Pittsburgh, 203 Lothrop St., Pittsburgh, PA, 15213, USA. loewen.nils@gmail.com.ORCID http://orcid.org/0000-0001-7167-1213
Shahid Beheshti University of Medical Sciences · IRUniversity of Pittsburgh · USBaqiyatallah University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Ethan A Rossi · 1989 to 2026
$17.8M
NEI NIH HHS P30 EY008098NIH CORE Grant P30 EY08098
6 · The paper itself

Abstract

purposeTo evaluate the association between baseline ocular variables and the widening of the anterior chamber angle by laser peripheral iridotomy (LPI) in primary angle closure suspects (PACS) using a new Fourier-domain swept-source anterior segment optical coherence tomography (FD-ASOCT).

methodSixty-six PACS eyes of 41 individuals were enrolled in this prospective interventional case series. An FD-ASOCT (Casia SS-1000 OCT; Tomey, Nagoya, Japan) was used to measure biometric baseline variables and at 1 month after the LPI. Paired t test was used to compare the difference between pre-and post-LPI measurements. Multivariate regression analysis was used to test for an association between baseline iris thickness and volume, anterior chamber depth and volume, and lens vault with a widening of the angle after an LPI. Changes in trabecular iris space area and angle opening distance after the LPI were main outcome measures.

resultsThe mean age of participants was 58.6 ± 8.7 years, 68.2% of whom were female. The angle opening distance, recess area, and trabecular iris surface area at 500 μm increased by 48 to 73% (all P < 0.001). Lens vault and iris volume did not change. A low anterior chamber volume and low iris volume were associated with angle greater deepening by LPI.

conclusionEyes with a shallow anterior chamber and thinner irises are more likely to experience angle opening from an LPI.

Indexed as

IridectomyAnterior ChamberFemaleFourier AnalysisGlaucoma, Angle-ClosureGonioscopyHumansIntraocular PressureIrisLaser TherapyMaleMiddle AgedProspective StudiesTomography, Optical CoherenceAnterior chamber volume, iris volume, CASIA OCTLaser peripheral iridotomy, swept-source anterior segment OCTPrimary angle closure suspect

Identifiers

PMID30073624
PMCPMC7809532
OpenAlexW2783185902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.