Evidence map›Paper›PMID 30073471›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018

Life satisfaction and pain interference in spine surgery patients before and after surgery: comparison between on-opioid and opioid-naïve patients.

Moona Kuronen, Hannu Kokki, Timo Nyyssönen, Sakari Savolainen, Merja Kokki

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Moona KuronenFaculty of Health Sciences, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Hannu KokkiFaculty of Health Sciences, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Timo NyyssönenDepartment of Orthopaedics, Traumatology and Hand Surgery, Kuopio University Hospital, Kuopio, Finland.
Sakari SavolainenNeuroCentre, Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
Merja KokkiFaculty of Health Sciences, School of Medicine, University of Eastern Finland, Kuopio, Finland. merja.kokki@kuh.fi.ORCID http://orcid.org/0000-0003-1501-7537

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePain has a negative impact on life satisfaction (LS). Our primary aims were to compare LS in on-opioid and opioid-naïve spine surgery patients and to evaluate whether surgery affects LS during the first 3 weeks after surgery.

methodsAfter informed consent 200 patients (99 on-opioid, 101 opioid-naïve; 112 male; aged 23-71 years) having elective spine surgery were enrolled. Their LS was evaluated using a four-item Life Satisfaction Scale (4-20, lower score more satisfied) and pain interference using Brief Pain Inventory (BPI)-questionnaire (0-10, lower score, less interference) before and 21 days after surgery.

resultsAt baseline LS was lower in the ON-OPIOID-group, mean LS-score 10.6 (SD 3.9), than that in the OPIOID-NAÏVE-group, 9.3 (3.0) (p = .027). At 3 weeks after surgery LS had increased in both groups compared to baseline (p < .001). However, LS was still lower in the ON-OPIOID-group, 9.1 (3.7) than that in the OPIOID-NAÏVE-group, 7.6 (2.7) (p = .005). Patients with lower LS experienced more pain interference pre- and post-operatively (p < .001). At 3 weeks the pain interference had decreased in both groups, in the ON-OPIOID-group from mean BPI-score 5.1 (2.0) to 3.0 (2.0) (p < .001) and in the OPIOID-NAÏVE-group from 4.0 (2.1) to 2.4 (2.3) (p < .001), but BPI-score was still higher in the ON-OPIOID-group (p = .045).

conclusionLife satisfaction increased and pain interference decreased in both groups after spine surgery. However, LS was lower and pain interference was more significant in on-opioid patients than that in opioid-naïve patients.

Indexed as

Pain MeasurementPersonal SatisfactionAcetaminophenAdultAgedAnalgesics, OpioidDrug CombinationsElective Surgical ProceduresFemaleHumansKetoprofenMaleMeloxicamMiddle AgedNaltrexoneOxycodoneAcetaminophenAnalgesics, Opioiddexketoprofen trometamolDrug CombinationsKetoprofenMeloxicamNaltrexoneOxycodoneoxycodone naltrexone combinationTromethamineLife satisfactionOpioid usePain interferenceSpine surgery

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.