Evidence map›Paper›PMID 30073454›Full record

SynthesisHepatology international2018

Liver resection versus transarterial chemoembolization for the initial treatment of Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma.

Biao Yang, Bo Zheng, MaoNan Yang, Zhu Zeng, FangYun Yang, Ji Pu, ChunLin Li, ZhengYin Liao

Abstract readComparative StudySystematic Review
PubMed Publisher
In one paragraph

Synthesis in Hepatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The Role of Gut Microbiota in Liver Regeneration After Partial Hepatectomy: New Evidence From Animal and Human Studies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  3. Article
  4. Article
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  9. State-of-the-art surgery for hepatocellular carcinoma.Langenbeck's archives of surgery · 2021
    Article
  10. Article
  11. Article
  12. Liver Resection Is Justified in Patients with BCLC Intermediate Stage Hepatocellular Carcinoma without Microvascular Invasion.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Biao YangDepartment of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, People's Republic of China. landayb@163.com.
Bo ZhengDepartment of Interventional Radiology, High-Tech Hospital, Zigong, People's Republic of China.
MaoNan YangDepartment of Oncology, LeShan Tradition Medicine Hospital, Leshan, People's Republic of China.
Zhu ZengDepartment of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, People's Republic of China.
FangYun YangDepartment of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, People's Republic of China.
Ji PuDepartment of Interventional Radiology, High-Tech Hospital, Zigong, People's Republic of China.
ChunLin LiDepartment of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, People's Republic of China.
ZhengYin LiaoDepartment of Abdominal Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, People's Republic of China. liaozhengyin@163.com.ORCID http://orcid.org/0000-0002-7010-7546

Funding

Science & Technology Department of Sichuan Province of China 2017SZ0014
6 · The paper itself

Abstract

aimsCurrent evidence supporting the efficacy of transarterial chemoembolization (TACE) in Barcelona Clinic Liver Cancer (BCLC)-B hepatocellular carcinoma (HCC) is controversial. The aim of this systematic review was to compare the benefits of liver resection (LR) versus TACE in BCLC-B HCC.

methodsWe conducted a comprehensive literature review of the EMBASE, PubMed, Google Scholar, and Chinese Biomedical Literature databases for retrospective or prospective studies evaluating the efficacy of LR and TACE for the treatment of BCLC-B HCC.

resultsEleven studies incorporating 3366 patients were included in this analysis. 1-year (RR 0.52 95% CI 0.43-0.63, p < 0.001; I

conclusionLiver resection had significant survival benefits over TACE in selected BCLC-B HCC patients in comparison to TACE. However, LR was associated with a significantly increased incidence of treatment-related mortality and infection compared to TACE.

Indexed as

Chemoembolization, TherapeuticHepatectomyCarcinoma, HepatocellularHumansLiver NeoplasmsNeoplasm StagingPrognosisSurvival AnalysisTreatment OutcomeBCLCHepatocellular carcinomaIntermediate stageResectionTransarterial chemoembolization

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.