Evidence map›Paper›PMID 30073151›Full record

ArticleFrontiers in cellular and infection microbiology2018

Moderate Dietary Protein Restriction Optimized Gut Microbiota and Mucosal Barrier in Growing Pig Model.

Xiyue Chen, Peixia Song, Peixin Fan, Ting He, Devin Jacobs, Crystal L Levesque, Lee J Johnston, Linbao Ji, Ning Ma, Yiqiang Chen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Phenotypic and Genomic Analysis of Swine-DerivedAnimals : an open access journal from MDPI · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Xiyue ChenState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Peixia SongState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Peixin FanState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Ting HeState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Devin JacobsDepartment of Animal Sciences, South Dakota State University, Brookings, SD, United States.
Crystal L LevesqueDepartment of Animal Sciences, South Dakota State University, Brookings, SD, United States.
Lee J JohnstonSwine Nutrition and Production, West Central Research and Outreach Center, University of Minnesota, Morris, MN, United States.
Linbao JiState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Ning MaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Yiqiang ChenState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Jie ZhangDepartment of Animal Husbandry and Veterinary, Beijing Vocational College of Agriculture, Beijing, China.
Jinshan ZhaoKey Laboratory of Animal Nutrition, College of Animal Science and Technology, Qingdao Agricultural University, Qingdao, China.
Xi MaState Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
China Agricultural University · CNSouth Dakota State University · USBeijing Health Vocational College · CNQingdao Agricultural University · CNThe University of Texas Southwestern Medical Center · USUniversity of Minnesota, Waseca · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Appropriate protein concentration is essential for animal at certain stage. This study evaluated the effects of different percentages of dietary protein restriction on intestinal health of growing pigs. Eighteen barrows were randomly assigned to a normal (18%), low (15%), and extremely low (12%) dietary protein concentration group for 30 days. Intestinal morphology and permeability, bacterial communities, expressions, and distributions of intestinal tight junction proteins, expressions of biomarkers of intestinal stem cells (ISCs) and chymous bacterial metabolites in ileum and colon were detected. The richness and diversity of bacterial community analysis with Chao and Shannon index were highest in the ileum of the 15% crude protein (CP) group. Ileal abundances of

Indexed as

AnimalsAnimals, NewbornColonDietary ProteinsGastrointestinal MicrobiomeIleumIntestinal MucosaSwineZonula Occludens-1 ProteinDietary ProteinsZonula Occludens-1 Proteindietary protein restrictiongrowing pigsintestinal microbiotaintestinal stem cellmucosal barrier

Identifiers

PMID30073151
PMCPMC6058046
OpenAlexW2882990710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.