Evidence map›Paper›PMID 30073140›Full record

ArticleRespiratory medicine case reports2018

A new

Keiki Yokoo, Gen Yamada, Hirofumi Chiba, Aki Ishikawa, Hiroko Morisaki, Hiroshi Saijo, Sayaka Kudoh, Yasuo Kitamura, Naoki Hirokawa, Masahiro Miyajima and 2 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Keiki YokooDepartment of Respiratory Medicine, Teine Keijinkai Hospital, Japan.
Gen YamadaDepartment of Respiratory Medicine, Teine Keijinkai Hospital, Japan.
Hirofumi ChibaDepartment of Respiratory Medicine and Allergology, Sapporo Medical University, Japan.
Aki IshikawaDepartment of Medical Genetics, Sapporo Medical University, Japan.
Hiroko MorisakiDepartment of Medical Genetics, Sakakibara Heart Institute, Japan (Formerly, Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute), Japan.
Hiroshi SaijoDepartment of Respiratory Medicine and Allergology, Sapporo Medical University, Japan.
Sayaka KudohDepartment of Respiratory Medicine, Kushiro City General Hospital, Japan.
Yasuo KitamuraDepartment of Respiratory Medicine, Kushiro City General Hospital, Japan.
Naoki HirokawaDepartment of Radiology, Sapporo Medical University, Japan.
Masahiro MiyajimaDepartment of Respiratory Surgery, Sapporo Medical University, Japan.
Atsushi WatanabeDepartment of Respiratory Surgery, Sapporo Medical University, Japan.
Hiroki TakahashiDepartment of Respiratory Medicine and Allergology, Sapporo Medical University, Japan.
Sapporo Medical University · JPKushiro City General Hospital · JPTeine Keijinkai Hospital · JPNational Cerebral and Cardiovascular Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case series of four siblings with hereditary hemorrhagic telangiectasia (HHT) and pulmonary arteriovenous malformations (PAVM). The patients' mother has HHT. Case 1: A 22-year-old man developed dyspnea and epistaxis. CT revealed a large PAVM, treated by segmentectomy. Case 2: A 27-year-old woman developed epistaxis and dyspnea. CT revealed three PAVMs, treated by partial resection. Case 3: A 20-year-old woman developed dyspnea. CT revealed multiple PAVMs, treated with endovascular occlusion of the largest one. Case 4: A 12-year-old woman developed epistaxis. CT revealed multiple PAVMs, observed without treatment. Genetic testing identified a new mutation, ENG c.1517T>C (p.Leu506Pro), in all patients and their mother. We suspect that HHT in these patients may be associated with this ENG mutation.

Indexed as

Hereditary hemorrhagic telangiectasiaOsler-Weber-Rendu diseasePulmonary arteriovenous malformation

Identifiers

PMID30073140
PMCPMC6068337
OpenAlexW2811396734

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.